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Monica Pillon Lab

Publications

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Selected Publications

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Pillon MC*,搂, Frazier MN搂, Dillard LB搂, Williams JG, Kocaman S, Krahn JM, Perera L, Hayne CK, Gordon J, Stewart ZD, Sobhany M, Deterding LJ, Hsu AL, Dandey VP, Borgnia MJ, Stanley RE*. 鈥淐ryo-EM Structures of the SARS-CoV-2 Endoribonuclease Nsp15.鈥 Nature Communications. 2021 January 27; 12 (1): 636. PMID: 33504779.

Pillon MC搂, Goslen KH搂, Gordon J, Wells ML, Williams JG, Stanley RE. 鈥淚t takes two Las1 HEPN endoribonuclease domains to cut the RNA correctly.鈥 The Journal of Biological Chemistry. 2020 May 1; 295 (18): 5857-5870. PMID: 32220933.

Pillon MC, Hsu AL, Krahn JM, Williams JG, Goslen KH, Sobhany M, Borgnia MJ, Stanley RE. 鈥淐ryo-EM Reveals Active Site Coordination Within a Multienzyme pre-rRNA Processing Complex.鈥 Nature Structural and Molecular Biology. 2019 September; 26 (9): 830-839. PMID: 31488907.

Pillon MC, Sobhany M, Stanley RE. 鈥淐haracterization of the Molecular Crosstalk within the Essential Grc3/Las1 pre-rRNA Processing Complex.鈥 RNA. 2018 May; 24 (5): 721-738. PMID: 29440475.

Pillon MC, Sobhany M, Borgnia MJ, Williams JG, Stanley RE. 鈥淕rc3 programs the essential endoribonuclease Las1 for specific RNA cleavage.鈥 Proceedings of the National Academy of Sciences of the United States of America. 2017 July 11; 114 (28): E5530-E5538. PMID: 28652339.

Pillon MC, Babu VMP, Randall JR, Cai J, Simmons LA, Sutton MD, Guarn茅 A. 鈥淭he sliding clamp tethers the MutL endonuclease domain to DNA.鈥 Nucleic Acids Research. 2015 December 15; 43 (22): 10746-10759. PMID: 26384423.

Pillon MC, Dubinsky M, Johnston RN, Liu SL, Guarn茅 A. 鈥淐haracterization of the defects in the ATP lid of E. coli MutL that cause transient hypermutability.鈥 DNA Repair. 2013 October; 12 (10): 864-869. PMID: 23916559.

Pillon MC, Miller JH, Guarn茅 A. 鈥淭he endonuclease domain of MutL interacts with the 尾 sliding clamp.鈥 DNA Repair. 2011 January 2; 10 (1): 87-93. PMID: 21050827.

Pillon MC, Lorenowicz JJ, Ukelmann M, Klocko AD, Mitchell RR, Chung YS, Modrich P, Walker GC, Simmons LA, Friedhoff P, Guarn茅 A. 鈥淪tructure of the endonuclease domain of MutL: unlicensed to cut.鈥 Molecular Cell. 2010 July 9; 39 (1): 145-151. PMID: 20603082.