Lee, S., Lee, S.B., Sung, N., Xu, W.W., Chang, C., Kim, H.E., Catic, A. and Tsai, F.T.F. (2023). Structural Basis of Impaired Disaggregase Function in the Oxidation-sensitive SKD3 Mutant Causing 3-Methylglutaconic Aciduria. Nature Commun. 14:2028. [] []
Lee, G., Kim, R.S., Lee, S.B., Lee, S. and Tsai, F.T.F. (2022). Deciphering the Mechanism and Function of Hsp100 Unfoldases from Protein Structure. Biochem. Soc. Trans. 50:1725-36. []
Mercado, J.M., Lee, S., Chang, C., Sung, N., Soong, L., Catic, A. and Tsai, F.T.F. (2022). Atomic Structure of the Leishmania spp. Hsp100 N-domain. Proteins 6:1242-6 []
Tsai, J.T., Sung, N., Lee, J., Chang, C., Lee, S., and Tsai, F.T.F. (2019) Crystal Structure of the YcjX Stress Protein Reveals a Ras-like GTP-binding Protein. J. Mol. Biol. 431:3179-90. []
Lee, S., Roh, S.H., Lee, J., Sung, N., Liu, J. and Tsai, F.T.F. (2019) Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation. Cell Rep. 26:29-36 []
Sung, N., Lee, J., Kim, J.-H., Chang, C., Joachimiak, A., Lee, S. and Tsai, F.T.F. (2016) Mitochondrial Hsp90 is a Ligand Activated Molecular Chaperone Coupling ATP Binding to Dimer Closure Through a Coiled-coil Intermediate. Proc. Natl. Acad. Sci. USA. 113:2952-2957. []
Lee, J., Kim, J.-H., Biter, A.B., Sielaff, B., Lee, S. and Tsai, F.T.F. (2013). Hsp70 is a Potent Activator of the Hsp104 AAA+ Motor. Proc. Natl. Acad. Sci. USA. 110:8513-8518. []
Biter, A.B., Lee, S., Sung, N. and Tsai, F.T.F. (2012). Structural Basis for Inter-subunit Signaling in a Protein Disaggregating Machine. Proc. Natl. Acad. Sci. USA. 109:12515-12520. []
Lee, S., Augustin, S., Tatsuta, T., Gerdes, F., Langer, T. and Tsai, F.T.F. (2011). Electron Cryomicroscopy Structure of a Membrane-anchored Mitochondrial AAA Protease. J. Biol. Chem. 286:4404-4411. []
Sielaff, B. and Tsai, F.T.F. (2010). The M-domain Controls the Hsp104 Protein-remodeling Activity in an Hsp70/Hsp40-dependent Manner. J. Mol. Biol. 402:30-37. []
Lee, S., Sielaff, B., Lee, J. and Tsai, F.T.F. (2010). CryoEM Structure of Hsp104 and Its Mechanistic Implication for Protein Disaggregation. Proc. Natl. Acad. Sci. USA. 107:8135-8140. []
Lee, S., Choi, J.-M. and Tsai, F.T.F. (2007). Visualizing the ATPase Cycle in a Protein Disaggregating Machine: Structural Basis for Substrate Binding by ClpB. Mol. Cell 25:261-271. []
Weibezahn, J., Tessarz, P., Schlieker, C., Zahn, R., Maglica, Z., Lee, S., Zentgraf, H., Weber-Ban, E., Dougan, D., Tsai, F.T.F., Mogk, A. and Bukau, B. (2004). Thermotolerance Requires Refolding of Aggregated Proteins by Substrate Translocation Through the Central Pore of ClpB. Cell 119:653-665. []
Commentaries by A.L. Horwich (2004) Cell 119:579-581. []; J. Shorter and S.L. Lindquist (2005) Nat. Struct. Mol. Biol. 12:4-6. []
Lee, S., Sowa, M.E., Watanabe, Y., Sigler, P.B., Chiu, W., Yoshida, M. and Tsai, F.T.F. (2003). The Structure of ClpB: A Molecular Chaperone that Rescues Proteins from an Aggregated State. Cell 115:229-240. []
Commentary by A. Mogk and B. Bukau (2004) Curr. Biol. 14:R78-R80. []
Tsai, F.T.F. and Sigler, P.B. (2000). Structural Basis of Preinitiation Complex Assembly on Human Pol II Promoters. EMBO J. 19:25-36. []
Cited in the "Advanced Information on the Nobel Prize in Chemistry 2006" by L. Thelander. []
