*Co-corresponding author; ¹co-first author
J. Kumar, L. Lackey, J.M. Waldern, A. Dey, A.M. Mustoe, K.M. Weeks, D.H. Mathews, A. Laederach. Quantitative prediction of variant effects on alternative splicing in MAPT using endogenous pre-messenger RNA structure probing. eLife, 2022, 11:e73888 ()
S.W. Olson, A.M.W. Turner, J.W. Arney, I. Saleem, C.A. Weidmann, D.M. Margolis, K.M. Weeks*, A.M. Mustoe*. Discovery of a large-scale, cell-state-responsive allosteric switch in the 7SK RNA using DANCE-MaP. Mol. Cell, 2022, 82:1708-1723.E10 ()
C.A. Weidmann, A.M. Mustoe, P.B. Jariwala, J.M. Calabrese, K.M. Weeks. Analysis of RNA–protein networks with RNP-MaP defines functional hubs on RNA. Nature Biotechnol., 2021, 39:347-356 ()
R.S. Dhindsa, B.R. Copeland, A.M. Mustoe, D.B. Goldstein. Natural selection shapes codon usage in the human genome. Am. J. Hum. Genet., 2020, 107: 83-95 ()
A.M. Mustoe, N.N. Lama, P.S. Irving, S.W. Olson, K.M. Weeks. RNA base pairing complexity in living cells visualized by correlated chemical probing. Proc. Natl. Acad. Sci. USA, 2019, 116: 24574-24582 ()
A.M. Mustoe*, M. Corley, A. Laederach, and K.M. Weeks*. mRNA structure regulates translation initiation: A mechanism exploited from bacteria to humans. Biochemistry, 2018, 57: 3537-3539. ()
A.M. Mustoe*¹, S. Busan¹, G.M. Rice¹, C.E. Hajdin, B.K. Peterson, V.M. Ruda, N. Kubica, R. Nutiu, J.L. Baryza, and K.M. Weeks*. Pervasive regulatory functions of mRNA structure revealed by high-resolution SHAPE probing. Cell, 2018, 173: 181-195. ()
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M. Corley, A. Solem, G. Phillips, L. Lackey, B. Ziehr, H.A. Vincent, A.M. Mustoe, S.B.V. Ramos, K.M. Weeks, N.J. Moorman, and A. Laederach. An RNA structure-mediated, post-transcriptional model of human a-1-antitrypsin expression. Proc. Natl. Acad. Sci. U.S.A., 2017, 114: E10244-E10253. ()
M. Daher¹, A.M. Mustoe¹, A. Morriss-Andrews¹, C. L. Brooks III, and N. G. Walter. Tuning RNA folding and function through rational design of junction topology. Nucleic Acids Res., 2017, 45: 9706-9715. ()
A. Krokhotin¹, A.M. Mustoe¹, K. M. Weeks, and N. V. Dokholyan. Direct identification of base-paired RNA nucleotides by correlated chemical probing. RNA, 2017, 23: 6-13. ()
C. A. Weidman¹, A.M. Mustoe¹, and K. M. Weeks. Direct duplex detection: an emerging tool in the RNA structural analysis toolbox. Trends Biochem. Sci, 2016, 41: 734-736. ()
A.M. Mustoe, H. M. Al-Hashimi, C. L. Brooks III. Secondary structure encodes a cooperative tertiary folding funnel in the Azoarcus ribozyme. Nucleic Acids Res., 2016, 44:402-412. ()
A.M. Mustoe, X. Liu, P. Lin, H. M. Al-Hashimi, C. A. Fierke, and C. L. Brooks III. Noncanonical secondary structure stabilizes human mitochondrial tRNASer(UCN) by reducing the entropic cost of tertiary folding. J. Amer. Chem. Soc., 2015, 137: 3592–3599. ()
A. Dickson, A.M. Mustoe, L. Salmon, and C.L. Brooks III. Efficient in-silico exploration of RNA interhelical conformations using Euler angles and WExplore. Nucleic Acids Res., 2014, 42: 12126- 12137. ()
A.M. Mustoe, C.L. Brooks III, and H.M. Al-Hashimi. Topological constraints are major determinants of tRNA tertiary structure and provide basis for tertiary folding cooperativity. Nucleic Acids Res., 2014, 42: 11792-11804. ()
L. R. Ganser, A.M. Mustoe, and H. M. Al-Hashimi. An RNA tertiary switch by modifying how helices are tethered. Genome Biol., 2014, 15: 425-428. ()
A.M. Mustoe, C. L. Brooks III, and H. M. Al-Hashimi. Hierarchy of RNA functional dynamics. Annu. Rev. Biochem., 2014, 83: 441-466. ()
A.M. Mustoe, H. M. Al-Hashimi, and C. L. Brooks III. Coarse-grained models reveal essential contributions of topological constraints to the conformational free energy of RNA bulges. J. Phys. Chem. B., 2014, 118: 2615–27. ()
K. C. Suddala, A. J. Rinaldi, J. Feng, A.M. Mustoe, C. D. Eichhorn, J. A. Liberman, J. E. Wedekind, H. M. Al-Hashimi, C. L. Brooks III, and N. G. Walter. Single transcriptional and translational preQ1 riboswitches adopt similar pre-folded ensembles that follow distinct folding pathways into the same ligand-bound structure. Nucleic Acids Res., 2013, 41: 10462-75. ()
A. R. Pah, R. Guimerà , A.M. Mustoe, and L. A. N. Amaral. Use of a global metabolic network to curate organismal metabolic networks. Sci. Rep., 2013, 3: 1695. ()
E. A. Dethoff, J. Chugh, A.M. Mustoe, and H. M. Al-Hashimi. Functional complexity and regulation through RNA dynamics. Nature, 2012, 482:322-330. ()
A.M. Mustoe, M. H. Bailor, R. Teixeira, C. L. Brooks III, and H. M. Al-Hashimi. New insights into the fundamental role of topological constraints as a determinant of two-way junction conformation. Nucleic Acids Res., 2012, 40: 892-904. (
M. H. Bailor¹, A.M. Mustoe¹, C. L. Brooks III, and H. M. Al-Hashimi. 3D maps of RNA interhelical junctions. Nature Protoc., 2011, 6:1536-45. ()
M. H. Bailor, A.M. Mustoe, C. L. Brooks III, and H. M. Al-Hashimi. Topological constraints: using RNA secondary structure to model 3D conformation, folding pathways, and dynamic adaptation. Curr. Opin. Struct. Biol., 2011, 21:296-305. ()
