Overview
The Zebrafish Genetic and Phenotyping Core provides expertise and equipment to support your experiments with zebrafish as an in vivo model. The Core can generate zebrafish with mutations in specific genes and engineer transgenic fish to monitor expression of genes of interest, mark cell type populations, proliferation and differentiation in live embryos. The Core can also assist with phenotypic analysis by preparing zebrafish for live imaging, histology, next generation sequencing, mass spectrometry or other biochemical assays. Design and performance of chemical screens to identify small molecules that cause or rescue a phenotype of interest in zebrafish embryos is also a core service.