Murugesan Palaniappan
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Murugesan Palaniappan
Assistant Professor
Positions
- Assistant Professor
-
Pathology & Immunology
Center for Drug Discovery
草榴社区入口
Houston, Texas United States
- Group Leader
-
DNA encoded chemical library screening
Center for Drug Discovery
草榴社区入口
- Member
-
Dan L Duncan Comprehensive Cancer Center
Education
- PhD from University of Madras
- 11/2007 - Chennai, India
- Postdoctoral Training at University of Michigan
- 08/2011 - Ann Arbor, Michigan United States
Professional Interests
- Breast cancer
- DNA encoded chemical library screening
- Drug Discovery and Development
Websites
Selected Publications
- Palaniappan M "." Biomedicines. 2024 Dec;12(Estrogen for the Treatment and Prevention of Breast Cancer):1-17.
- Palaniappan M*, Nguyen L, Grimm SL Xi Y, Xia Z, Li W, Coarfa C "." PloS One. 2019; Pubmed PMID:
- Palaniappan M, Edwards D, Creighton CJ, Medina D, Conneely OM. "." PLoS One. 2018 Mar; Pubmed PMID:
- Modukuri RK, Monsivais D, Li F, Palaniappan M, Bohren KM, Tan Z, Ku AF, Wang Y, Madasu C, Li JY, Tang S, Miklossy G, Palmer SS, Young DW, Matzuk MM. "." J Med Chem. 2023; Pubmed PMID:
- Judge A, Sankaran B, Hu L, Palaniappan M, Birgy A, Prasad BVV, Palzkill T. "." PNAS. 2024 Mar 19;121(12)::e2313513121. Pubmed PMID:
- Madasu C, Liao Z, Parks SE, Sharma KL, Bohren KM, Ye Q, Li F, Palaniappan M, Tan Z, Yuan F, Creighton CJ, Tang S, Masand RP, Guan X, Young DW, Monsivais D, Matzuk MM. "." PNAS. 2024 May 8;121(19):e2322934121.
- Ku AF, Sharma KL, Ta HM, Sutton CM, Bohren KM, Wang Y, Chamakuri S, Chen R, Hakenjos JM, Jimmidi R, Kent K, Li F, Li JY, Ma L, Madasu C, Palaniappan M, Palmer SS, Qin X, Robers MB, Sankaran B, Tan Z, Young DW, Teng M, Kim C, Matzuk MM. "." Science. 2024 May 23;384(6698):885-890. Pubmed PMID:
- Lu S, Hu L, Lin H, Judge A, Rivera P, Palaniappan M, Sankaran B, Wang J, Prasad BVV, Palzkill T. "." Nat Commun. 2022; Pubmed PMID:
- Park S, Fan J, Chamakuri S, Palaniappan M, Sharma K, Qin X, Wang J, Tan Z, Judge A, Hu L, Sankaran B, Li F, Prasad BVV, Matzuk MM, Palzkill T. "." J Med Chem.. 2024 Jan 11;67(1):620-642.. Pubmed PMID:
- Li JY, Miklossy G, Modukuri RK, Bohren KM, Yu Z, Palaniappan M, Faver JC, Riehle K, Matzuk MM, Simmons N. "." Bioconjug Chem.. 2019 Aug; Pubmed PMID:
- Du HC, Simmons N, Faver JC, Yu Z, Palaniappan M, Riehle K, Matzuk MM. "." Org Lett. 2019; Pubmed PMID:
- Palaniappan M, Menon KM. "." Mol Endocrinol. 2010; Pubmed PMID:
- Palaniappan M, Menon KM "." Mol Endocrinol. 2012 Jul; Pubmed PMID:
- Will MA, Palaniappan M, Peegel H, Kayampilly P, Menon KM "." Fertil Steril. 2012 Jul; Pubmed PMID:
- Palaniappan M, Menon KM. "." Biol Reprod. 2009; Pubmed PMID:
- Muthusamy T, Murugesan P, Srinivasan C, Balasubramanian K. "." Mol Cell Biochem. 2011 Jun; Pubmed PMID:
- Palaniappan M, Menon B, Menon KM "." Mol Cell Endocrinol.. 2013; Pubmed PMID:
- Taylor DM, Anglin J, Park S, Ucisik MN, Faver JC, Simmons N, Jin Z, Palaniappan M, Nyshadham P, Li F, Campbell J, Hu L, Sankaran B, Prasad BVV, Huang H, Matzuk MM, Palzkill T. "." ACS Infect Dis.. 2020 May;6 Pubmed PMID:
- Ye Q, Belabed H, Wang Y, Yu Z, Palaniappan M, Li JY, Kalovidouris SA, MacKenzie KR, Teng M, Young DW, Fujihara Y, Matzuk MM. "." Andrology. 2022; Pubmed PMID:
Memberships
- The Endocrine Society
- American Association for Cancer Research (AACR)
- Active Member
Funding
- Development of Next-Generation Estrogen Receptor Mutant Inhibitors for Endocrine Resistant Metastatic Breast Cancer - #RP220524
- $769,179.00 (03/01/2022 - 02/28/2025) Grant funding from CPRIT
- Development of a Precision Drug to target Y537S Mutant Estrogen Receptor in Metastatic Breast Cancer - #R03CA259664
- $160,000.00 (12/13/2021 - 11/30/2023) Grant funding from NIH/NCI
Skills
- SCIENTIST
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