Melanie Samuel, Ph.D.
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Melanie Samuel, Ph.D.
Associate Professor
Positions
- Associate Professor
-
Department of Neuroscience, Huffington Center on Aging
草榴社区入口
Houston, TX US
- CPRIT Scholar
-
Cancer Prevention Research Institute of Texas
- Member
-
Dan L Duncan Comprehensive Cancer Center
草榴社区入口
Houston, Texas United States
Education
- PhD from Washington University School of Medicine
- St. Louis, Missouri United States
- Postdoctoral Fellowship at Harvard
- Cambridge, Massachusetts United States
- BS from the University of Idaho
- Moscow, Idaho United States
- Summa Cum Laude, Biochemistry and Microbiology
- BA from the University of Idaho
- Moscow, United States
- Summa Cum Laude, English
Professional Interests
- Discovery of new neural development molecules and pathways.
- Development of nanoscopic imaging tools and techniques for circuit analysis.
- Novel genetic models of human neural diseases
- Computational approaches to circuit mapping.
Professional Statement
The Samuel Lab seeks to tackle a central question: what make humans resilient to challenges? To solve this mystery, we focus on the nervous system because it gives rise to our individuality and underlies all of our thoughts and behavior. These abilities arise from startlingly diverse populations of cells called neurons and glia. Each of these cell types must form and connect properly in order for the brain to function. But often these processes fail, resulting in neural disease. We aim to decipher the genes and molecules that control neural fate, connectivity, and resiliency in the hope that we can one day manipulate them to prevent, or even reverse, neural disease.Websites
Selected Publications
- Sarin S. Zuniga-Sanchez E, Kurmangaliyev Y, Cousins H, Patel M, Hernandez J, Zhang K, Morey M, Samuel MA, Sanes M1*, Zipursky LS. "." Neuron. 2018 Mar 22;98(1):109-126.E8. Pubmed PMID:
- Samuel MA, Voinescu PE, Lilley BN, de Cabo R, Foretz M, Viollet B, Pawlyk B, Sandberg MA, Vavvas DG, Sanes JR. "." Nat Neurosci. 2014 Sep 17;17:1190-1197. Pubmed PMID:
- Albrecht NE, Alevy J, Jiang D, Burger CA, Liu BI, Li F, Wang J, Kim SY, Hsu CW, Kalaga S, Udensi U, Asomugha C, Bohat R, Gaspero A, Justice MJ, Westenskow PD, Yamamoto S, Seavitt JR, Beaudet AL, Dickinson ME, Samuel MA. "." Cell Reports. 2018 Aug 28;24(9):2506-2519. Pubmed PMID:
- Alevy J, Burger CA, Albrecht NE, Jiang D, Samuel MA. "." Neurochem Int.. 2019 Oct;129 Pubmed PMID:
- Greer P, Samuel MA. "." Neuron. 2019 Sep 25;103(6):959-963. Pubmed PMID:
- Jiang D, Burger CA, Casasent A, Albrecht NE, Li F, Samuel MA. "." J Comp Neuro.. 2019 Oct 31;528(5):729-755. Pubmed PMID:
- Li F, Jiang D, Samuel, MA. "." Neural Development.. 2019 Dec 30;14(1):12. Pubmed PMID:
- Burger CA, Jiang D, Li F, Samuel MA. "." Frontiers in Neural Circuits. 2020 Oct 16;14:64. Pubmed PMID:
- Burger CA, Alevy J, Casasent AK, Jiang D, Albrecht NE, Liang JH, Hirano AA, Brecha NC, Samuel MA. "." Elife. 2020 May 7; Pubmed PMID:
- Burger CA, Albrecht NE, Jiang D, Liang JH, Poche RA, Samuel MA. "." Cell Reports. 2021 Feb 2;34(5) Pubmed PMID:
- Burger CA, Jiang D, Mackin RD, Samuel MA. "." Developmental Biology. 2021 Apr 10;476:218-239. Pubmed PMID:
- D'Souza SP, Swygart DI, Wienbar SR, Upton BA, Zhang KX, Mackin RD, Casasent AK, Samuel MA, Schwartz GW, Lang RA "." J Comp Neurol. 2021 Nov 7; Pubmed PMID:
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