Maria Elena Bottazzi, Ph.D.
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Maria Elena Bottazzi, Ph.D.
Sr. Associate Dean, National School of Tropical Medicine
Phone
Phone
Positions
- Sr. Associate Dean, National School of Tropical Medicine
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草榴社区入口
Houston, Texas United States
- Professor
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Departments of Pediatrics (Tropical Medicine) and Molecular Virology and Microbiology, Integrative Molecular and Biomedical Sciences Program, and Translational Biology and Molecular Medicine Program
草榴社区入口
Houston, Texas United States
- Co-Director
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Texas Children's Hospital Center for Vaccine Development
Houston, Texas United States
- Distinguished Professor of Biology
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Baylor University
- Adjunct Professor
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Department of Bioengineering
Rice University
- Editor-in-Chief
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Current Tropical Medicine Reports
Springer US
Education
- PhD from University Of Florida
- 05/1995 - Gainesville, Florida United States
- Licenciatura en Microbiolog铆a y from Universidad Nacional Aut贸noma de Honduras
- 05/1989 - Tegucigalpa, Departamento Francisco Moraz谩n Honduras
- Post-Doctoral Fellowship at University Of Pennsylvania
- 05/2001 - Philadelphia, PA United States
- Post-Doctoral Fellowship at University Of Miami Hospital And Clinics
- 05/1998 - Miami, FL United States
- Fellowship at American Association for the Advancement of Science Leshner Leadership Institute
- 02/2017 - Washington, DC
Websites
Selected Publications
- Nyon MP, Du L, Tseng CK, Seid CA, Pollet J, Naceanceno KS, Agrawal A, Algaissi A, Peng BH, Tai W, Jiang S, Bottazzi ME, Strych U, Hotez PJ "." Vaccine. 2018; Pubmed PMID:
- Diemert D, Campbell D, Brelsford J, Leasure C, Li G, Peng J, Zumer M, Younes N, Bottazzi ME, Mejia R, Pritchard DI, Hawdon JM, Bethony JM "." Open Forum Infect Dis. 2018; Pubmed PMID:
- Villanueva-Lizama LE, Cruz-Chan JV, Aguilar-Cetina ADC, Herrera-Sanchez LF, Rodriguez-Perez JM, Rosado-Vallado ME, Ramirez-Sierra MJ, Ortega-Lopez J, Jones K, Hotez P, Bottazzi ME, Dumonteil E. "." PLoS negl trop dis. 2018; Pubmed PMID:
- Bottazzi ME "." J Helminthol. 2015; Pubmed PMID:
- McKenna ML, McAtee S, Bryan PE, Jeun R, Ward T, Kraus J, Bottazzi ME, Hotez PJ, Flowers CC, Mejia R "." Am J Trop Med Hyg. 2017; Pubmed PMID:
- Chen WH, Chag SM, Poongavanam MV, Biter AB, Ewere EA, Rezende W, Seid CA, Hudspeth EM, Pollet J, McAtee CP, Strych U, Bottazzi ME, Hotez PJ "." J Pharm Sci. 2017; Pubmed PMID:
- Lustigman S, Makepeace BL, Klei TR, Babayan SA, Hotez P, Abraham D, Bottazzi ME "." Trends in Parasit. 2018; Pubmed PMID:
- Jiang D, Zhan B, Mayor RS, Gillespie P, Keegan B, Bottazzi ME, Hotez P "." Mol. Biochem. Parasitol.. 2011 May;177(1):42-8. Pubmed PMID:
- Dumonteil E, Bottazzi ME, Zhan B, Heffernan MJ, Jones K, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Lee BY, Bacon KM, Fleischer B, Slingsby B, Cravioto MB, Tapia-Conyer R, Hotez PJ "." Expert Rev Vaccines. 2012 Sep;11(9):1043-55. Pubmed PMID:
- Plieskatt JL, Rezende WC, Olsen CM, Trefethen JM, Joshi SB, Middaugh CR, Hotez PJ, Bottazzi ME "." Hum Vaccin Immunother. 2012 Jun;8(6):765-76. Pubmed PMID:
- Roovers K, Davey G, Zhu X, Bottazzi ME, Assoian RK "." Mol. Biol. Cell. 1999 Oct;10(10):3197-204. Pubmed PMID:
- Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, Jones K, Keegan B, Hotez PJ, Loukas A "." FASEB J.. 2009 Sep;23(9):3007-19. Pubmed PMID:
- Bottazzi ME, Miles AP, Diemert D, Hotez PJ "." Expert Rev Vaccines. 2006 Apr;5(2):189-98. Pubmed PMID:
- Williamson AL, Lustigman S, Oksov Y, Deumic V, Plieskatt J, Mendez S, Zhan B, Bottazzi ME, Hotez PJ, Loukas A "." Infect. Immun.. 2006 Feb;74(2):961-7. Pubmed PMID:
- Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ "." FASEB J.. 2005 Oct;19(12):1743-5. Pubmed PMID:
- Cai S, He F, Samra HS, de la Maza LM, Bottazzi ME, Joshi SB, Middaugh CR "." Mol. Pharm..;6(5):1553-61. Pubmed PMID:
- Bottazzi ME, Goodenow MM, Moscovici MG, Moscovici C "." Oncogene. 1993 Mar;8(3):731-6. Pubmed PMID:
- Hotez PJ, Dumonteil E, Woc-Colburn L, Serpa JA, Bezek S, Edwards MS, Hallmark CJ, Musselwhite LW, Flink BJ, Bottazzi ME "." PLoS Negl Trop Dis. 2012 May;6(5):e1498. Pubmed PMID:
- Bottazzi ME, Buzzai M, Zhu X, Desdouets C, Br茅chot C, Assoian RK "." Mol. Cell. Biol.. 2001 Nov;21(22):7607-16. Pubmed PMID:
- Ambrose MR, Bottazzi ME, Goodenow MM "." DNA Cell Biol.. 1995 Aug;14(8):701-7. Pubmed PMID:
- Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, Bethony JM, Loukas A, Roy M, Hotez PJ "." Vaccine. 2005 Sep 15;23(39):4754-64. Pubmed PMID:
- Mathias DK, Plieskatt JL, Armistead JS, Bethony JM, Abdul-Majid KB, McMillan A, Angov E, Aryee MJ, Zhan B, Gillespie P, Keegan B, Jariwala AR, Rezende W, Bottazzi ME, Scorpio DG, Hotez PJ, Dinglasan RR "." Infect. Immun.. 2012 Apr;80(4):1606-14. Pubmed PMID:
- Goud GN, Deumic V, Gupta R, Brelsford J, Zhan B, Gillespie P, Plieskatt JL, Tsao EI, Hotez PJ, Bottazzi ME "." Protein Expr. Purif.. 2012 Jun;83(2):145-51. Pubmed PMID:
- Bonaf茅 N, Zhan B, Bottazzi ME, Perez OA, Koski RA, Asojo OA "." Acta Crystallogr. Sect. F Struct. Biol. Cryst. 2010 Nov 1;66:1487-9. Pubmed PMID:
- Kehn K, Berro R, Alhaj A, Bottazzi ME, Yeh WI, Klase Z, Van Duyne R, Fu S, Kashanchi F "." Oncogene. 2007 Aug 2;26(35):5060-9. Pubmed PMID:
- Zhan B, Santiago H, Keegan B, Gillespie P, Xue J, Bethony J, de Oliveira LM, Jiang D, Diemert D, Xiao SH, Jones K, Feng X, Hotez PJ, Bottazzi ME "." Parasite Immunol.. 2012 Aug;34(41495):404-11. Pubmed PMID:
- Lee BY, Bacon KM, Bottazzi ME, Hotez PJ "." Lancet Infect Dis. 2013 Apr;13(4):342-8. Pubmed PMID:
- Hotez PJ, Arora S, Bethony J, Bottazzi ME, Loukas A, Correa-Oliveira R, Brooker S "." Adv. Exp. Med. Biol.. 2005;568:135-44. Pubmed PMID:
- Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S "." N. Engl. J. Med.. 2004 Aug 19;351(8):799-807. Pubmed PMID:
- Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Buss P "." PLoS Med.. 2005 Mar;2(3):e67. Pubmed PMID:
- Fujiwara RT, Bethony J, Bueno LL, Wang Y, Ahn SY, Samuel A, Bottazzi ME, Hotez P, Mendez S "." ;1(3):123-8. Pubmed PMID:
- Hotez PJ, Dumonteil E, Heffernan MJ, Bottazzi ME "." Adv. Exp. Med. Biol.. 2013;764:41286. Pubmed PMID:
- Bottazzi ME, Brown AS "." Expert Rev Vaccines. 2008 Dec;7(10):1481-92. Pubmed PMID:
- Lee BY, Bacon KM, Wateska AR, Bottazzi ME, Dumonteil E, Hotez PJ "." Hum Vaccin Immunother. 2012 Sep 1;8(9):1293-301. Pubmed PMID:
- Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, Ranjit N, Lustigman S, Oksov Y, Hotez P "." Infect. Immun.. 2010 Apr;78(4):1552-63. Pubmed PMID:
- Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Diemert D, Loukas A "." Trends Parasitol.. 2006 Jul;22(7):327-31. Pubmed PMID:
- Jariwala AR, Oliveira LM, Diemert DJ, Keegan B, Plieskatt JL, Periago MV, Bottazzi ME, Hotez PJ, Bethony JM "." Expert Rev Vaccines. 2010 Oct;9(10):1219-30. Pubmed PMID:
- Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, Essiet-Gibson I, Chung-Debose S, Xiao S, Knox D, Meagher M, Inan M, Correa-Oliveira R, Vilk P, Sheph "." Int. J. Parasitol.. 2003 Sep 30;33(11):1245-58. Pubmed PMID:
- Fujiwara RT, Zhan B, Mendez S, Loukas A, Bueno LL, Wang Y, Plieskatt J, Oksov Y, Lustigman S, Bottazzi ME, Hotez P, Bethony JM "." Clin. Vaccine Immunol.. 2007 Mar;14(3):281-7. Pubmed PMID:
- Jiang S, Bottazzi ME, Du L, Lustigman S, Tseng CT, Curti E, Jones K, Zhan B, Hotez PJ "." Expert Rev Vaccines. 2012 Dec;11(12):1405-13. Pubmed PMID:
- Hotez PJ, Bottazzi ME, Dumonteil E, Valenzuela JG, Kamhawi S, Ortega J, Ponce de Leon Rosales S, Betancourt Cravioto M, Tapia-Conyer R "." PLoS Negl Trop Dis. 2012 Mar;6(3):e1497. Pubmed PMID:
- Hotez PJ, Diemert D, Bacon KM, Beaumier C, Bethony JM, Bottazzi ME, Brooker S, Couto AR, Freire Mda S, Homma A, Lee BY, Loukas A, Loblack M, Morel CM, Oliveira RC, Russell PK "." Vaccine. 2013 Apr 18;31:B227-32. Pubmed PMID:
- Hotez PJ, Bottazzi ME, Franco-Paredes C, Ault SK, Periago MR "." PLoS Negl Trop Dis. 2008;2(9):e300. Pubmed PMID:
- Bacon KM, Hotez PJ, Kruchten SD, Kamhawi S, Bottazzi ME, Valenzuela JG, Lee BY "." Vaccine. 2013 Jan 7;31(3):480-6. Pubmed PMID:
- Kehn K, Deng L, de la Fuente C, Strouss K, Wu K, Maddukuri A, Baylor S, Rufner R, Pumfery A, Bottazzi ME, Kashanchi F "." Retrovirology. 2004;1:6. Pubmed PMID:
- Franco-Paredes C, Bottazzi ME, Hotez PJ "." PLoS Negl Trop Dis. 2009;3(7):e470. Pubmed PMID:
- Fujiwara RT, Loukas A, Mendez S, Williamson AL, Bueno LL, Wang Y, Samuel A, Zhan B, Bottazzi ME, Hotez PJ, Bethony JM "." Vaccine. 2006 Jan 23;24(4):501-9. Pubmed PMID:
- Loukas A, Bethony JM, Mendez S, Fujiwara RT, Goud GN, Ranjit N, Zhan B, Jones K, Bottazzi ME, Hotez PJ "." PLoS Med.. 2005 Oct;2(10):e295. Pubmed PMID:
- Ghosh K, Wu W, Antoine AD, Bottazzi ME, Valenzuela JG, Hotez PJ, Mendez S "." J. Infect. Dis.. 2006 Jan 1;193(1):155-62. Pubmed PMID:
- Kehn K, Fuente Cde L, Strouss K, Berro R, Jiang H, Brady J, Mahieux R, Pumfery A, Bottazzi ME, Kashanchi F "." Oncogene. 2005 Jan 20;24(4):525-40. Pubmed PMID:
- Bottazzi ME, Assoian RK "." Trends Cell Biol.. 1997 Sep;7(9):348-52. Pubmed PMID:
- Seelamgari A, Maddukuri A, Berro R, de la Fuente C, Kehn K, Deng L, Dadgar S, Bottazzi ME, Ghedin E, Pumfery A, Kashanchi F "." Front. Biosci.. 2004 Sep 1;9:2388-413. Pubmed PMID:
- Bottazzi ME, Zhu X, B枚hmer RM, Assoian RK "." J. Cell Biol.. 1999 Sep 20;146(6):1255-64. Pubmed PMID:
- Wu K, Bottazzi ME, de la Fuente C, Deng L, Gitlin SD, Maddukuri A, Dadgar S, Li H, Vertes A, Pumfery A, Kashanchi F "." J. Biol. Chem.. 2004 Jan 2;279(1):495-508. Pubmed PMID:
- Kehn K, Berro R, de la Fuente C, Strouss K, Ghedin E, Dadgar S, Bottazzi ME, Pumfery A, Kashanchi F "." Front. Biosci.. 2004 Sep 1;9:2347-72. Pubmed PMID:
- Campi-Azevedo AC, Gazzinelli G, Bottazzi ME, Teixeira-Carvalho A, Corr锚a-Oliveira R, Caldas IR "." Microbes Infect.. 2007 Oct;9(41621):1493-9. Pubmed PMID:
- Gunter SM, Jones KM, Seid CA, Essigmann HT, Zhan B, Strych U, Bottazzi ME, Hotez PJ, Brown EL "." J Parasit. 2017; Pubmed PMID:
Projects
- Coronavirus vaccines
- New vaccines against coronaviruses including Covid-19
- Chagas Disease and Leishmaniasis Vaccine
- Development for a new therapeutic vaccine for Chagas disease. Current efforts focus on the development of two vaccine candidate antigens that will ultimately comprise the first therapeutic vaccine for Chagas disease.
- Human Hookworm Vaccine
- Development of a vaccine for the more than 700 million people suffering from hookworm in the world today. Vaccine currently in phase 1 clinical trials.
- Schistosomiasis Vaccine
- Schistosomiasis afflicts over 200 million people around the globe and is the deadliest disease among the seven most prevalent NTDs, killing an estimated 280,000 people annually.
- Multivalent Anthelmintic Vaccine Discovery
- A panhelmintic vaccine to prevent ascariasis (roundworm) and trichuris (whipworm), soil-transmitted helminths afflicting hundreds of millions of people around the world.
- Development of a novel adjuvant for vaccine sparing
- To develop a highly effective and safe protein adjuvant in a simple aqueous formulation that requires a much lower dose of antigen and that can be administered to humans to boost their immune response.
Memberships
- American Society of Tropical Medicine and Hygiene
- Member
- American Society for Microbiology
Languages
Italian, Spanish, Portuguese
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