Positions
- Associate Professor
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Molecular and Human Genetics
草榴社区入口
Houston, TX US
- Associate Professor
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Molecular & Cellular Biology
草榴社区入口
- Director
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Genomic & RNA Profiling Core
草榴社区入口
- Director
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Integrated Genomics Core
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Diabetes Research Center
- Director - Genomic Profiling Shared Resource
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Dan L Duncan Comprehensive Cancer Center
草榴社区入口
Houston, Texas United States
- Co-Director
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Functional Genomics and Microbiome Core
Texas Medical Center Digestive Disease Center
- Director, Genomic and RNA Profiling Shared Resource
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Dan L Duncan Comprehensive Cancer Center
草榴社区入口
Houston, Texas United States
Addresses
- BCM-MD Anderson Hall (Office)
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Room: BCMA-333e
Houston, TX 77030
United States
Education
- BA from Baylor University
- 01/1989 - Waco, TX United States
- PhD from University Of Houston
- 01/1994 - Houston, TX United States
- Post-Doctoral Fellowship at University Of Maryland At College Park
- 01/1998 - College Park, MD United States
Professional Interests
- Genomic and RNA profiling utilizing cutting edge whole genome/transcriptome technologies to understand cancer and metastases
Professional Statement
I am interested in genomic profiling technologies and how these technologies can be used to answer questions in cancer, especially the changes that occur at the genomic, transcriptomic, and regulatory levels. For example, utilizing high throughput sequencing platforms we can assay the entire genome with applications like mRNA-seq, smallRNA-seq, ChIP-seq, whole genome sequencing, etc. I am particularly interested in genomic changes that result in progression to metastasis in cancer models. These changes can be chromosomal (copy number gains and losses) that affect coding genes and, importantly, non-coding RNAs or microRNAs.As Director of the Genomic & RNA Profiling Core at BCM, I support high throughput genomic and RNA profiling technologies for members of the BCM community and throughout the Texas Medical Center. We collaborate with users from the Dan L Duncan Cancer Center, The BCM Diabetes Research Center, The Intellectual and Developmental Disabilities Research Center, and the Texas Medical Center Digestive Disease Center.
Websites
Genomic & RNA Profiling Core Facility
Selected Publications
- Ku BJ, Kim TH, Lee JH, Buras ED, White LD, Stevens RD, Ilkayeva OR, Bain JR, Newgard CB, Demayo FJ, Jeong JW "." PLoS ONE. 2012;7(8):e42915. Pubmed PMID:
- Li J, Harris RA, Cheung SW, Coarfa C, Jeong M, Goodell MA, White LD, Patel A, Kang SH, Shaw C, Chinault AC, Gambin T, Gambin A, Lupski JR, Milosavljevic A "." PLoS Genet.. 2012 May;8(5):e1002692. Pubmed PMID:
- Homan EP, Rauch F, Grafe I, Lietman C, Doll JA, Dawson B, Bertin T, Napierala D, Morello R, Gibbs R, White L, Miki R, Cohn DH, Crawford S, Travers R, Glorieux FH, Lee B "." J. Bone Miner. Res.. 2011 Dec;26(12):2798-803. Pubmed PMID:
- Mullany LK, Fan HY, Liu Z, White LD, Marshall A, Gunaratne P, Anderson ML, Creighton CJ, Xin L, Deavers M, Wong KK, Richards JS "." Oncogene. 2011 Aug 11;30(32):3522-36. Pubmed PMID:
- Franco HL, Lee KY, Rubel CA, Creighton CJ, White LD, Broaddus RR, Lewis MT, Lydon JP, Jeong JW, DeMayo FJ "." Biol. Reprod.. 2010 May;82(5):991-9. Pubmed PMID:
- Franco HL, Lee KY, Broaddus RR, White LD, Lanske B, Lydon JP, Jeong JW, DeMayo FJ "." Biol. Reprod.. 2010 Apr;82(4):783-90. Pubmed PMID:
- Oshima J, Magner DB, Lee JA, Breman AM, Schmitt ES, White LD, Crowe CA, Merrill M, Jayakar P, Rajadhyaksha A, Eng CM, del Gaudio D "." Hum. Genet.. 2009 Sep;126(3):411-23. Pubmed PMID:
- Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ "." Proc. Natl. Acad. Sci. U.S.A.. 2009 May 26;106(21):8677-82. Pubmed PMID:
- Van den Veyver IB, Patel A, Shaw CA, Pursley AN, Kang SH, Simovich MJ, Ward PA, Darilek S, Johnson A, Neill SE, Bi W, White LD, Eng CM, Lupski JR, Cheung SW, Beaudet AL "." Prenat. Diagn.. 2009 Jan;29(1):29-39. Pubmed PMID:
- Bi W, Breman AM, Venable SF, Eng PA, Sahoo T, Lu XY, Patel A, Beaudet AL, Cheung SW, White LD "." Prenat. Diagn.. 2008 Oct;28(10):943-9. Pubmed PMID:
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