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Email

jpang@bcm.edu

Positions

Associate Professor

Department of Ophthalmology
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Houston, Texas United States

Addresses

Neurosensory Center (Office)

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Houston, TX 77030
United States
Phone: (713) 798-5527

Education

MD from Medical school, Xi'an Jiaotong University

Xi'an, P. R. China

PhD from Medical school, Xi'an Jiaotong University

Xi'an, P. R. China

Postdoctoral Fellowship at ²ÝÁñÉçÇøÈë¿Ú

01/2000 - Houston, Texas United States

Neurology

Postdoctoral Fellowship at ²ÝÁñÉçÇøÈë¿Ú

Houston, Texas United States

Ophthalmology

Professional Interests

• Complete identification of all retinal neurons with light-evoked activities and morphological features
• Retinal ion channels, synapses and neuronal circuitry
• Mechanosensitive ion channels in retinal function and diseases

Professional Statement

My work focuses on retinal visual signaling in physiological and pathological conditions. I characterize retinal photoreceptors, bipolar cells, amacrine cells, and ganglion cells with light-evoked activities and single-cell immunofluorescence. Based on such neuronal identities, I further study the signaling between photoreceptors and bipolar cells and synapses among bipolar cells, amacrine cells, and ganglion cells, primarily by using one- to eight-cell patch-clamp technologies, in conjunction with genetic engineering, electron microscopy, confocal microscopy, and immunocytochemistry. Built on these physiological data, my study further explores the role of mechanical-sensitive ion channels in normal retinal visual functions and the pathogenesis of glaucoma, traumatic retinal injury, and other pressure-related retinal disorders.

Websites

Selected Publications

• Frankfort BJ, Khan AK, Tse DY, Chung I, Pang JJ, Yang Z, Gross RL, Wu SM "." Invest. Ophthalmol. Vis. Sci.. 2013;54(1):762-70. Pubmed PMID:
• Pang JJ, Gao F, Lem J, Bramblett DE, Paul DL, Wu SM "." Proc. Natl. Acad. Sci. U.S.A.. 2010 Jan 5;107(1):395-400. Pubmed PMID:
• Pang JJ, Gao F, Wu SM "." J. Neurosci.. 2003 Jul 9;23(14):6063-73. Pubmed PMID:
• Pang JJ, Gao F, Wu SM "." J. Neurosci.. 2002 Jun 1;22(11):4693-701. Pubmed PMID:

Memberships

Association for Research in Vision and Ophthalmology

Member

Society for Neuroscience

Member

Royal Society of Medicine (London)

Member