Helen E Heslop, MD, DSc (Hon)

Picture

Helen E Heslop, MD, DSc (Hon)

Professor

Phone

832-824-4662

Email

hheslop@bcm.edu

Positions

Professor: Departments of Medicine and Pediatrics
Section of Hematology-Oncology
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Houston, TX US

Director - Center for Cell and Gene Therapy: ��
Houston, TX US
Texas Children's Hospital Houston Methodist

Dan L Duncan Chair: ��

Leader, Cancer Cell & Gene Therapy: Dan L Duncan Comprehensive Cancer Center
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Houston, Texas United States

Addresses

TX Childs Feigin Ctr (Office)
: Room: TXFC-164006
Houston, TX 77030
United States
Phone: (832) 824-4671
hheslop@bcm.edu

Houston Methodist Hospital (Clinic)
: 6565 Fannin St., Suite 800
Houston, TX 77030
United States
Phone: (713) 394-6250

Houston Methodist Hospital (Hospital)
: 6565 Fannin St., Suite 800
Houston, TX 77030
United States
Phone: (713) 394-6250

Education

M.D. from University Of Otago, New Zealand: 01/1990 - Otago, New Zealand

Advanced Training from Royal Free Hospital: 01/1986 - London, United Kingdom

Advanced Training from Christchurch Hospital: 01/1982 - Christchurch, New Zealand

M.B.,Ch.B. from University Of Otago, New Zealand: 01/1980 - Otago, New Zealand

Certifications

Fellow of the Royal Australasian College of Physicians (FRACP)

Fellow of the Royal College of Pathologists of Australasia (FRCPA)

Honors & Awards

President: Foundation for Accreditation Cell Therapy (01/2012 - 12/2015)

President: American Society of Blood and Marrow Transplantation (02/2008 - 02/2009)

President: American Society of Gene and Cell Therapy (05/2017 - 05/2018)

Member: NCI Subcomittee A (08/2014 - 08/2020)

Chair: BMT-CTN Steering Committee (01/2020 - 01/2022)

Elected: Association of American Physicians (03/2004)

Elected: National Academy of Medicine (10/2021)

Professional Interests

Cell and Gene Therapy

Professional Statement

Helen Heslop is a physician-scientist engaged in translational research focusing on adoptive immunotherapy with gene-modified effector cells, to improve hemopoietic stem cell transplantation and cancer therapy. A key step in this strategy has been the translation of laboratory findings to Phase I and II clinical trials, as exemplified by studies of Epstein Barr virus-induced lymphoproliferative disease (EBV-LPD), a fatal complication in about 15% of recipients of unrelated or mismatched family member bone marrow transplants in the early 1990s. In collaboration with Dr Cliona Rooney, she developed methods for early diagnosis of this disease and procedures for generating cytotoxic T lymphocytes (CTLs) from bone marrow donors. These studies were the first to demonstrate that antigen-specific cytotoxic T cells could eradicate an established malignancy and because the cells were genetically marked, we obtained definitive evidence of cell expansion, trafficking to tumor sites and decade-long persistence. Subsequent protocols have extended this approach to Hodgkin's Disease, NHL and nasopharyngeal cancer. She has an additional focus in reconstituting antiviral immunity post transplant in collaboration with Drs. Rooney, Leen and Bollard and is currently leading an NHLBI-funded multicenter trial of allogeneic multivirus specific T cells. She therefore has extensive experience in developing and conducting transplant studies and cell and gene therapy studies under IND and has also obtained orphan drug designation for my initial study. Other areas of research focus in collaboration include identification of novel tumor antigens and genetic modification of CTLs to overcome tumor evasion strategies. In collaboration with Drs. Brenner, Dotti, Savoldo, Gottschalk and Ahded group they are also evaluating if transduction of CTLs with chimeric antigen receptors can allow targeting of CD19+ve, CD30+ve and her2neu+ve malignancies.

Websites

Selected Publications

Bollard CM, Gottschalk S, Leen AM, Weiss H, Straathof KC, Carrum G, Khalil M, Wu MF, Huls MH, Chang CC, Gresik MV, Gee AP, Brenner MK, Rooney CM, Heslop HE "." Blood. 2007 Oct 15;110(8):2838-45. Pubmed PMID:
Heslop HE, Slobod KS, Pule MA, Hale GA, Rousseau A, Smith CA, Bollard CM, Liu H, Wu MF, Rochester RJ, Amrolia PJ, Hurwitz JL, Brenner MK, Rooney CM "." Blood. 2010 Feb 4;115(5):925-35. Pubmed PMID:
Bollard CM, Rooney CM, Heslop HE "." Nat Rev Clin Oncol. 2012 Aug 14;9(9):510-9. Pubmed PMID:
Di Stasi A, Tey SK, Dotti G, Fujita Y, Kennedy-Nasser A, Martinez C, Straathof K, Liu E, Durett AG, Grilley B, Liu H, Cruz CR, Savoldo B, Gee AP, Schindler J, Krance RA, Heslop HE, Spencer DM, Rooney CM, Brenner MK "." N. Engl. J. Med.. 2011 Nov 3;365(18):1673-83. Pubmed PMID:

Louis CU, Savoldo B, Dotti G, Pule M, Yvon E, Myers GD, Rossig C, Russell HV, Diouf O, Liu E, Liu H, Wu MF, Gee AP, Mei Z, Rooney CM, Heslop HE, Brenner MK "." Blood. 2011 Dec 1;118(23):6050-6. Pubmed PMID:
Pule MA, Savoldo B, Myers GD, Rossig C, Russell HV, Dotti G, Huls MH, Liu E, Gee AP, Mei Z, Yvon E, Weiss HL, Liu H, Rooney CM, Heslop HE, Brenner MK "." Nat. Med.. 2008 Nov;14(11):1264-70. Pubmed PMID:
Pulè MA, Straathof KC, Dotti G, Heslop HE, Rooney CM, Brenner MK "." Mol. Ther.. 2005 Nov;12(5):933-41. Pubmed PMID:
Heslop HE "." Blood. 2011 Apr 21;117(16):4165-6. Pubmed PMID:
Macmillan ML, Couriel D, Weisdorf DJ, Schwab G, Havrilla N, Fleming TR, Huang S, Roskos L, Slavin S, Shadduck RK, Dipersio J, Territo M, Pavletic S, Linker C, Heslop HE, Joachim Deeg H, Blazar BR "." Blood. 2007 Mar 15;109(6):2657-62. Pubmed PMID:
Heslop HE "." J. Immunol. Methods. 1978;22(41337):389-91. Pubmed PMID:
Gottlieb DJ, Brenner MK, Heslop HE, Bianchi AC, Bello-Fernandez C, Mehta AB, Newland AC, Galazka AR, Scott EM, Hoffbrand AV "." Br. J. Cancer. 1989 Oct;60(4):610-5. Pubmed PMID:
Wagner HJ, Bollard CM, Vigouroux S, Huls MH, Anderson R, Prentice HG, Brenner MK, Heslop HE, Rooney CM "." Cancer Gene Ther.. 2004 Feb;11(2):81-91. Pubmed PMID:
Lanyi A, Li B, Li S, Talmadge CB, Brichacek B, Davis JR, Kozel BA, Trask B, van den Engh G, Uzvolgyi E, Stanbridge EJ, Nelson DL, Chinault C, Heslop H, Gross TG, Seemayer TA, Klein G, Purtilo DT, Sumegi J "." Genomics. 1997 Jan 1;39(1):55-65. Pubmed PMID:
Vera JF, Brenner LJ, Gerdemann U, Ngo MC, Sili U, Liu H, Wilson J, Dotti G, Heslop HE, Leen AM, Rooney CM "." J. Immunother.. 2010 Apr;33(3):305-15. Pubmed PMID:
Bollard CM, Rössig C, Calonge MJ, Huls MH, Wagner HJ, Massague J, Brenner MK, Heslop HE, Rooney CM "." Blood. 2002 May 1;99(9):3179-87. Pubmed PMID:
Louis CU, Paulino AC, Gottschalk S, Bertuch AA, Chintagumpala M, Heslop HE, Russell HV "." J. Pediatr. Hematol. Oncol.. 2007 Jul;29(7):500-5. Pubmed PMID:
Hale GA, Heslop HE, Krance RA, Brenner MA, Jayawardene D, Srivastava DK, Patrick CC "." Bone Marrow Transplant.. 1999 Feb;23(3):277-82. Pubmed PMID:
Gahn B, Siller-Lopez F, Pirooz AD, Yvon E, Gottschalk S, Longnecker R, Brenner MK, Heslop HE, Aguilar-Cordova E, Rooney CM "." Int. J. Cancer. 2001 Sep 1;93(5):706-13. Pubmed PMID:
Fletcher BD, Heslop HE, Kaste SC, Bodner S "." Pediatr Radiol. 1998 Jul;28(7):492-6. Pubmed PMID:
Lee TC, Savoldo B, Barshes NR, Rooney CM, Heslop HE, Gee AP, Caldwell Y, Scott JD, Goss JA "." Clin Transplant.;20(3):389-93. Pubmed PMID:
Heslop HE, Brenner MK, Krance RA, Bowman L, Cunningham JM, Richardson S, Alexander B, Heideman R, Boyett JM, Srivastava DK, Marcus SG, Berenson R, Heimfeld S, Brown S "." Hum. Gene Ther.. 1996 Mar 20;7(5):655-67. Pubmed PMID:
Heslop HE, Hickton CM, Laird E, Tait JD, Doig JR, Beard EJ "." Scand J Haematol. 1986 Jul;37(1):71-3. Pubmed PMID:
Heslop HE, Rooney CM, Rill DR, Krance RA, Brenner MK "." Cancer Detect. Prev.. 1996;20(2):108-13. Pubmed PMID:
Rooney CM, Smith CA, Ng CY, Loftin S, Li C, Krance RA, Brenner MK, Heslop HE "." Lancet. 1995 Jan 7;345(8941):41530. Pubmed PMID:
Ahmed N, Heslop HE "." Curr. Opin. Hematol.. 2006 Jul;13(4):254-9. Pubmed PMID:
Chakraborty R, Mahendravada A, Perna SK, Rooney CM, Heslop HE, Vera JF, Savoldo B, Dotti G "." Haematologica. 2013 Apr;98(4):533-7. Pubmed PMID:
Heslop HE, Benaim E, Brenner MK, Krance RA, Stricklin LM, Rochester RJ, Billing R "." Lancet. 1995 Sep 23;346(8978):805-6. Pubmed PMID:
Bear AS, Morgan RA, Cornetta K, June CH, Binder-Scholl G, Dudley ME, Feldman SA, Rosenberg SA, Shurtleff SA, Rooney CM, Heslop HE, Dotti G "." Mol. Ther.. 2012 Feb;20(2):246-9. Pubmed PMID:
Heslop HE "." Mol. Ther.. 2010 Apr;18(4):661-2. Pubmed PMID:
Wimperis JZ, Gottlieb D, Duncombe AS, Heslop HE, Prentice HG, Brenner MK "." J. Immunol.. 1990 Jan 15;144(2):541-7. Pubmed PMID:
Foster AE, Okur FV, Biagi E, Lu A, Dotti G, Yvon E, Savoldo B, Carrum G, Andreeff M, Goodell MA, Heslop HE, Brenner MK "." Mol. Cancer. 2009;8:106. Pubmed PMID:
Amrolia PJ, Muccioli-Casadei G, Yvon E, Huls H, Sili U, Wieder ED, Bollard C, Michalek J, Ghetie V, Heslop HE, Molldrem JJ, Rooney CM, Schlinder J, Vitetta E, Brenner MK "." Blood. 2003 Sep 15;102(6):2292-9. Pubmed PMID:
Foster AE, Okur FV, Biagi E, Lu A, Dotti G, Yvon E, Savoldo B, Carrum G, Goodell MA, Heslop HE, Brenner MK "." Leukemia. 2010 Mar;24(3):563-72. Pubmed PMID:
Heslop HE, Gottlieb DJ, Reittie JE, Bello-Fernandez C, Meager A, Prentice HG, Brenner MK "." Br. J. Haematol.. 1989 Jun;72(2):122-6. Pubmed PMID:
Ahmed N, Leung KS, Rosenblatt H, Bollard CM, Gottschalk S, Myers GD, Carrum G, Heslop HE, Brenner MK, Krance RA "." Biol. Blood Marrow Transplant.. 2008 Nov;14(11):1298-304. Pubmed PMID:
Heslop HE, Fitzgerald PH, Beard ME "." Cancer. 1987 Mar 1;59(5):1036-9. Pubmed PMID:
Smith FS, Rencher SD, Heslop HE, Hurwitz JL "." Cancer Immunol. Immunother.. 1995 Aug;41(2):104-10. Pubmed PMID:
Falkenburg JH, Heslop HE, Barrett AJ "." Biol. Blood Marrow Transplant.. 2008 Jan;14(1):136-41. Pubmed PMID:
Gottschalk S, Bollard CM, Straathof KC, Louis CU, Savoldo B, Dotti G, Brenner MK, Heslop HE, Rooney CM "." Ernst Schering Found Symp Proc. 2006;(4):69-82. Pubmed PMID:
Myers GD, Krance RA, Weiss H, Kuehnle I, Demmler G, Heslop HE, Bollard CM "." Bone Marrow Transplant.. 2005 Dec;36(11):1001-8. Pubmed PMID:
Bollard CM, Huls MH, Buza E, Weiss H, Torrano V, Gresik MV, Chang J, Gee A, Gottschalk SM, Carrum G, Brenner MK, Rooney CM, Heslop HE "." 2006 Jan;6(4):342-7. Pubmed PMID:
Roskrow MA, Rooney CM, Heslop HE, Brenner MK, Krance RA, Gresik MV, McClain K, Aguilar LK, Grilley B, Rob E, Carrum G "." Hum. Gene Ther.. 1998 May 20;9(8):1237-50. Pubmed PMID:
Heslop H, Rooney C, Brenner M, Krance R, Carrum G, Gahn B, Bollard C, Khan S, Gee A, Popat U, Gresik M, Przepiorka D, Kuehnle I, Grilley B "." Hum. Gene Ther.. 2000 Jul 1;11(10):1465-75. Pubmed PMID:
Heslop HE, Brenner MK, Rooney C, Krance RA, Roberts WM, Rochester R, Smith CA, Turner V, Sixbey J, Moen R "." Hum. Gene Ther.. 1994 Mar;5(3):381-97. Pubmed PMID:
Heslop HE, Rooney CM "." Immunol. Rev.. 1997 Jun;157:217-22. Pubmed PMID:
Fujita Y, Rooney CM, Heslop HE "." Bone Marrow Transplant.. 2008 Jan;41(2):193-8. Pubmed PMID:
Gottschalk S, Heslop HE, Rooney CM "." Leuk. Lymphoma. 2005 Jan;46(1):41284. Pubmed PMID:
Bollard CM, Kuehnle I, Leen A, Rooney CM, Heslop HE "." Biol. Blood Marrow Transplant.. 2004 Mar;10(3):143-55. Pubmed PMID:
Smith CA, Ng CY, Loftin SK, Li C, Heslop HE, Brenner MK, Rooney CM "." Leuk. Lymphoma. 1996 Oct;23(41337):213-20. Pubmed PMID:
Rooney CM, Aguilar LK, Huls MH, Brenner MK, Heslop HE "." Curr. Top. Microbiol. Immunol.. 2001;258:221-9. Pubmed PMID:
Amrolia PJ, Muccioli-Casadei G, Huls H, Adams S, Durett A, Gee A, Yvon E, Weiss H, Cobbold M, Gaspar HB, Rooney C, Kuehnle I, Ghetie V, Schindler J, Krance R, Heslop HE, Veys P, Vitetta E, Brenner MK "." Blood. 2006 Sep 15;108(6):1797-808. Pubmed PMID:
Brenner MK, Heslop HE "." Curr. Opin. Immunol.. 2010 Apr;22(2):251-7. Pubmed PMID:
Bollard CM, Savoldo B, Rooney CM, Heslop HE "." Acta Haematol.. 2003;110(41308):139-48. Pubmed PMID:
Huls MH, Rooney CM, Heslop HE "." Acta Haematol.. 2003;110(41308):149-53. Pubmed PMID:
Tey SK, Bollard CM, Heslop HE "." Immunol. Cell Biol.. 2006 Jun;84(3):281-9. Pubmed PMID:
Louis CU, Straathof K, Bollard CM, Ennamuri S, Gerken C, Lopez TT, Huls MH, Sheehan A, Wu MF, Liu H, Gee A, Brenner MK, Rooney CM, Heslop HE, Gottschalk S "." J. Immunother..;33(9):983-90. Pubmed PMID:
Cruz CR, Hanley PJ, Liu H, Torrano V, Lin YF, Arce JA, Gottschalk S, Savoldo B, Dotti G, Louis CU, Leen AM, Gee AP, Rooney CM, Brenner MK, Bollard CM, Heslop HE "." Cytotherapy. 2010 Oct;12(6):743-9. Pubmed PMID:
Shaffer DR, Sheehan AM, Yi Z, Rodgers CC, Bollard CM, Brenner MK, Rooney CM, Heslop HE, Gottschalk S "." Pediatr Blood Cancer. 2012 Oct;59(4):758-61. Pubmed PMID:
Hale GA, Tong X, Benaim E, Cunningham JM, Heslop HE, Horwiz EM, Leung W, Rochester RJ, Shearer PD, Srivastava DK, Woodard JP, Bowman LC "." Bone Marrow Transplant.. 2001 Jan;27(2):155-62. Pubmed PMID:
Samuelson S, Sandmaier BM, Heslop HE, Popat U, Carrum G, Champlin RE, Storb R, Prchal JT, Gooley TA, Joachim Deeg H "." Br. J. Haematol.. 2011 Apr;153(1):76-82. Pubmed PMID:
Heslop BF, Heslop HE "." Transplantation. 1979 Aug;28(2):144-8. Pubmed PMID:
Melenhorst JJ, Leen AM, Bollard CM, Quigley MF, Price DA, Rooney CM, Brenner MK, Barrett AJ, Heslop HE "." Blood. 2010 Nov 25;116(22):4700-2. Pubmed PMID:
Gottschalk S, Ng CY, Perez M, Smith CA, Sample C, Brenner MK, Heslop HE, Rooney CM "." Blood. 2001 Feb 15;97(4):835-43. Pubmed PMID:
Straathof KC, Pulè MA, Yotnda P, Dotti G, Vanin EF, Brenner MK, Heslop HE, Spencer DM, Rooney CM "." Blood. 2005 Jun 1;105(11):4247-54. Pubmed PMID:
Ramos CA, Asgari Z, Liu E, Yvon E, Heslop HE, Rooney CM, Brenner MK, Dotti G "." Stem Cells. 2010 Jun;28(6):1107-15. Pubmed PMID:
Krance R, Heslop HE, Mahmoud H, Ribeiro R, Douglass E, Hurwitz C, Santana V, Kun L, Horowitz MM, Brenner MK "." Bone Marrow Transplant.. 1993 Jan;11(1):33-6. Pubmed PMID:
Shafer JA, Cruz CR, Leen AM, Ku S, Lu A, Rousseau A, Heslop HE, Rooney CM, Bollard CM, Foster AE "." Leuk. Lymphoma. 2010 May;51(5):870-80. Pubmed PMID:
Foster AE, Dotti G, Lu A, Khalil M, Brenner MK, Heslop HE, Rooney CM, Bollard CM "." J. Immunother.. 2008 Jun;31(5):500-5. Pubmed PMID:
Jones RB, Anasetti C, Appel P, DiPersio J, Heslop H, Lemaistre F, Silver S, Sirilla J, Stiff P "." Biol. Blood Marrow Transplant.. 2006 May;12(5):594-7. Pubmed PMID:
Lacuesta K, Buza E, Hauser H, Granville L, Pule M, Corboy G, Finegold M, Weiss H, Chen SY, Brenner MK, Heslop HE, Rooney CM, Bollard CM "." J. Immunother..;29(3):250-60. Pubmed PMID:
Savoldo B, Huls MH, Liu Z, Okamura T, Volk HD, Reinke P, Sabat R, Babel N, Jones JF, Webster-Cyriaque J, Gee AP, Brenner MK, Heslop HE, Rooney CM "." Blood. 2002 Dec 1;100(12):4059-66. Pubmed PMID:
Brenner M, Krance R, Heslop HE, Santana V, Ihle J, Ribeiro R, Roberts WM, Mahmoud H, Boyett J, Moen RC "." Hum. Gene Ther.. 1994 Apr;5(4):481-99. Pubmed PMID:
Heslop HE "." Hematology Am Soc Hematol Educ Program. 2005;260-6. Pubmed PMID:
Ferrara JL, Anasetti C, Stadtmauer E, Antin J, Wingard J, Lee S, Levine J, Schultz K, Appelbaum F, Negrin R, Giralt S, Bredeson C, Heslop H, Horowitz M "." Biol. Blood Marrow Transplant.. 2007 Nov;13(11):1268-85. Pubmed PMID:
Hale GA, Heslop HE, Bowman LC, Rochester RA, Pui CH, Brenner MK, Krance RA "." Bone Marrow Transplant.. 1999 Oct;24(7):735-9. Pubmed PMID:
Kohn DB, Dotti G, Brentjens R, Savoldo B, Jensen M, Cooper LJ, June CH, Rosenberg S, Sadelain M, Heslop HE "." Mol. Ther.. 2011 Mar;19(3):432-8. Pubmed PMID:
Kuehnle I, Huls MH, Liu Z, Semmelmann M, Krance RA, Brenner MK, Rooney CM, Heslop HE "." Blood. 2000 Feb 15;95(4):1502-5. Pubmed PMID:
Savoldo B, Ramos CA, Liu E, Mims MP, Keating MJ, Carrum G, Kamble RT, Bollard CM, Gee AP, Mei Z, Liu H, Grilley B, Rooney CM, Heslop HE, Brenner MK, Dotti G "." J. Clin. Invest.. 2011 May 2;121(5):1822-6. Pubmed PMID:
Popat U, Carrum G, May R, Lamba R, Krance RA, Heslop HE, Brenner MK "." Bone Marrow Transplant.. 2005 Jun;35(12):1127-32. Pubmed PMID:
Savoldo B, Rooney CM, Quiros-Tejeira RE, Caldwell Y, Wagner HJ, Lee T, Finegold MJ, Dotti G, Heslop HE, Goss JA "." Am. J. Transplant.. 2005 Mar;5(3):566-72. Pubmed PMID:
Heslop HE, Savoldo B, Rooney CM "." Best Pract Res Clin Haematol. 2004 Sep;17(3):401-13. Pubmed PMID:
Mathew P, Bozeman P, Krance RA, Brenner MK, Heslop HE "." Bone Marrow Transplant.. 1994 Feb;13(2):221-3. Pubmed PMID:
Sun W, Popat U, Hutton G, Zang YC, Krance R, Carrum G, Land GA, Heslop H, Brenner M, Zhang JZ "." Brain. 2004 May;127:996-1008. Pubmed PMID:
Cohen JI, Jaffe ES, Dale JK, Pittaluga S, Heslop HE, Rooney CM, Gottschalk S, Bollard CM, Rao VK, Marques A, Burbelo PD, Turk SP, Fulton R, Wayne AS, Little RF, Cairo MS, El-Mallawany NK, Fowler D, Sportes C, Bishop MR, Wilson W, Straus SE "." Blood. 2011 Jun 2;117(22):5835-49. Pubmed PMID:
Straathof KC, Leen AM, Buza EL, Taylor G, Huls MH, Heslop HE, Rooney CM, Bollard CM "." J. Immunol.. 2005 Sep 15;175(6):4137-47. Pubmed PMID:
Lin YF, Lairson DR, Chan W, Du XL, Leung KS, Kennedy-Nasser AA, Martinez CA, Heslop HE, Brenner MK, Krance RA "." Pediatr Blood Cancer. 2011 Jan;56(1):143-51. Pubmed PMID:
Heslop HE "." J. Immunother..;29(4):365-6. Pubmed PMID:
Kennedy-Nasser AA, Bollard CM, Myers GD, Leung KS, Gottschalk S, Zhang Y, Liu H, Heslop HE, Brenner MK, Krance RA "." Biol. Blood Marrow Transplant.. 2008 Nov;14(11):1245-52. Pubmed PMID:
Kennedy-Nasser AA, Leung KS, Mahajan A, Weiss HL, Arce JA, Gottschalk S, Carrum G, Khan SP, Heslop HE, Brenner MK, Bollard CM, Krance RA "." Biol. Blood Marrow Transplant.. 2006 Dec;12(12):1277-84. Pubmed PMID:
Yotnda P, Zompeta C, Heslop HE, Andreeff M, Brenner MK, Marini F "." Hum. Gene Ther.. 2004 Dec;15(12):1229-42. Pubmed PMID:
Okur FV, Yvon E, Biagi E, Dotti G, Carrum G, Heslop H, Mims MP, Fratantoni JC, Peshwa MV, Li L, Brenner MK "." Cytotherapy. 2011 Oct;13(9):1128-39. Pubmed PMID:
Brenner MK, Wulf GG, Rill DR, Luo KL, Goodell MA, Mei Z, Kuehnle I, Brown MP, Pule M, Heslop HE, Krance RA "." Ann. N. Y. Acad. Sci.. 2003 May;996:80-8. Pubmed PMID:
Quintarelli C, Vera JF, Savoldo B, Giordano Attianese GM, Pule M, Foster AE, Heslop HE, Rooney CM, Brenner MK, Dotti G "." Blood. 2007 Oct 15;110(8):2793-802. Pubmed PMID:
Gao X, Xue Z, Xing J, Lee DY, Gottschalk SM, Heslop HE, Bollard CM, Wong ST "." Acad Radiol. 2010 Apr;17(4):479-88. Pubmed PMID:
Rooney CM, Smith CA, Heslop HE "." Mol Med Today. 1997 Jan;3(1):24-30. Pubmed PMID:
Williams LL, Rooney CM, Conley ME, Brenner MK, Krance RA, Heslop HE "." Lancet. 1993 Sep 4;342(8871):587-8. Pubmed PMID:
Salsman VS, Chow KK, Shaffer DR, Kadikoy H, Li XN, Gerken C, Perlaky L, Metelitsa LS, Gao X, Bhattacharjee M, Hirschi K, Heslop HE, Gottschalk S, Ahmed N "." PLoS ONE. 2011;6(5):e20267. Pubmed PMID:
Dotti G, Heslop HE "." Cytotherapy. 2005;7(3):262-72. Pubmed PMID:
Heslop HE "." Baillieres Clin. Haematol.. 1994 Mar;7(1):135-51. Pubmed PMID:
Lamba R, Carrum G, Myers GD, Bollard CM, Krance RA, Heslop HE, Brenner MK, Popat U "." Bone Marrow Transplant.. 2005 Nov;36(9):797-802. Pubmed PMID:
Bollard CM, Aguilar L, Straathof KC, Gahn B, Huls MH, Rousseau A, Sixbey J, Gresik MV, Carrum G, Hudson M, Dilloo D, Gee A, Brenner MK, Rooney CM, Heslop HE "." J. Exp. Med.. 2004 Dec 20;200(12):1623-33. Pubmed PMID:
Leen AM, Christin A, Myers GD, Liu H, Cruz CR, Hanley PJ, Kennedy-Nasser AA, Leung KS, Gee AP, Krance RA, Brenner MK, Heslop HE, Rooney CM, Bollard CM "." Blood. 2009 Nov 5;114(19):4283-92. Pubmed PMID:
Leen AM, Heslop HE "." Br. J. Haematol.. 2008 Oct;143(2):169-79. Pubmed PMID:
Quintarelli C, Dotti G, De Angelis B, Hoyos V, Mims M, Luciano L, Heslop HE, Rooney CM, Pane F, Savoldo B "." Blood. 2008 Sep 1;112(5):1876-85. Pubmed PMID:
Gerdemann U, Katari U, Christin AS, Cruz CR, Tripic T, Rousseau A, Gottschalk SM, Savoldo B, Vera JF, Heslop HE, Brenner MK, Bollard CM, Rooney CM, Leen AM "." Mol. Ther.. 2011 Dec;19(12):2258-68. Pubmed PMID:
Nunes E, Heslop H, Fernandez-Vina M, Taves C, Wagenknecht DR, Eisenbrey AB, Fischer G, Poulton K, Wacker K, Hurley CK, Noreen H, Sacchi N "." Hum. Immunol.. 2011 Dec;72(12):1214-6. Pubmed PMID:
Nunes E, Heslop H, Fernandez-Vina M, Taves C, Wagenknecht DR, Eisenbrey AB, Fischer G, Poulton K, Wacker K, Hurley CK, Noreen H, Sacchi N "." Blood. 2011 Dec 1;118(23):e180-3. Pubmed PMID:
Micklethwaite KP, Savoldo B, Hanley PJ, Leen AM, Demmler-Harrison GJ, Cooper LJ, Liu H, Gee AP, Shpall EJ, Rooney CM, Heslop HE, Brenner MK, Bollard CM, Dotti G "." Blood. 2010 Apr 1;115(13):2695-703. Pubmed PMID:
Wagner HJ, Rooney CM, Heslop HE "." Biol. Blood Marrow Transplant.. 2002;8(1):41282. Pubmed PMID:
Rill DR, Santana VM, Roberts WM, Nilson T, Bowman LC, Krance RA, Heslop HE, Moen RC, Ihle JN, Brenner MK "." Blood. 1994 Jul 15;84(2):380-3. Pubmed PMID:
Heslop HE, Brenner MK, Rooney CM "." N. Engl. J. Med.. 1994 Sep 8;331(10):679-80. Pubmed PMID:
Rooney CM, Loftin SK, Holladay MS, Brenner MK, Krance RA, Heslop HE "." Br. J. Haematol.. 1995 Jan;89(1):98-103. Pubmed PMID:
Rooney CM, Heslop HE, Brenner MK "." Vox Sang.. 1998;74:497-8. Pubmed PMID:
Heslop HE, Bianchi AC, Cordingley FT, Turner M, Chandima W, De Mel CP, Hoffbrand AV, Brenner MK "." J. Exp. Med.. 1990 Dec 1;172(6):1729-34. Pubmed PMID:
Gottlieb DJ, Prentice HG, Heslop HE, Bello-Fernandez C, Bianchi AC, Galazka AR, Brenner MK "." Blood. 1989 Nov 15;74(7):2335-42. Pubmed PMID:
Bianchi AC, Heslop HE, Drexler HG, Cordingley FT, Turner M, De Mel WC, Hoffbrand AV, Brenner MK "." Nouv Rev Fr Hematol. 1988;30(41400):317-9. Pubmed PMID:
Yotnda P, Onishi H, Heslop HE, Shayakhmetov D, Lieber A, Brenner M, Davis A "." Gene Ther.. 2001 Jun;8(12):930-7. Pubmed PMID:
Reittie JE, Gottlieb D, Heslop HE, Leger O, Drexler HG, Hazlehurst G, Hoffbrand AV, Prentice HG, Brenner MK "." Blood. 1989 Apr;73(5):1351-8. Pubmed PMID:
Ringwald-Smith KA, Heslop HE, Krance RA, Mackert PW, Hancock ML, Stricklin LM, Bowman LC, Hale GA "." Bone Marrow Transplant.. 2002 Jul;30(2):125-30. Pubmed PMID:
Hoyos V, Savoldo B, Quintarelli C, Mahendravada A, Zhang M, Vera J, Heslop HE, Rooney CM, Brenner MK, Dotti G "." Leukemia. 2010 Jun;24(6):1160-70. Pubmed PMID:
Bianchi AC, Heslop HE, Veys P, Macey M, Holland M, Prentice HG, Brenner MK "." Br. J. Haematol.. 1989 Dec;73(4):468-74. Pubmed PMID:
Louis CU, Straathof K, Bollard CM, Gerken C, Huls MH, Gresik MV, Wu MF, Weiss HL, Gee AP, Brenner MK, Rooney CM, Heslop HE, Gottschalk S "." Blood. 2009 Mar 12;113(11):2442-50. Pubmed PMID:
Pui CH, Relling MV, Rivera GK, Hancock ML, Raimondi SC, Heslop HE, Santana VM, Ribeiro RC, Sandlund JT, Mahmoud HH "." Leukemia. 1995 Dec;9(12):1990-6. Pubmed PMID:
Savoldo B, Rooney CM, Di Stasi A, Abken H, Hombach A, Foster AE, Zhang L, Heslop HE, Brenner MK, Dotti G "." Blood. 2007 Oct 1;110(7):2620-30. Pubmed PMID:
Heslop HE, Li C, Krance RA, Loftin SK, Rooney CM "." Blood. 1994 Mar 15;83(6):1706-8. Pubmed PMID:
Liu Z, Savoldo B, Huls H, Lopez T, Gee A, Wilson J, Brenner MK, Heslop HE, Rooney CM "." Recent Results Cancer Res.. 2002;159:123-33. Pubmed PMID:
Roskrow MA, Suzuki N, Gan Y, Sixbey JW, Ng CY, Kimbrough S, Hudson M, Brenner MK, Heslop HE, Rooney CM "." Blood. 1998 Apr 15;91(8):2925-34. Pubmed PMID:
Heslop HE "." Blood. 2012 Mar 15;119(11):2436-8. Pubmed PMID:
Voo KS, Fu T, Wang HY, Tellam J, Heslop HE, Brenner MK, Rooney CM, Wang RF "." J. Exp. Med.. 2004 Feb 16;199(4):459-70. Pubmed PMID:
Ngo MC, Rooney CM, Howard JM, Heslop HE "." Hum. Mol. Genet.. 2011 Apr 15;20:R93-9. Pubmed PMID:
Martinez CA, Shah S, Shearer WT, Rosenblatt HM, Paul ME, Chinen J, Leung KS, Kennedy-Nasser A, Brenner MK, Heslop HE, Liu H, Wu MF, Hanson IC, Krance RA "." J. Allergy Clin. Immunol.. 2012 Jan;129(1):176-83. Pubmed PMID:
Hanley PJ, Shaffer DR, Cruz CR, Ku S, Tzou B, Liu H, Demmler-Harrison G, Heslop HE, Rooney CM, Gottschalk S, Bollard CM "." Cytotherapy. 2011 Sep;13(8):976-86. Pubmed PMID:
Fujita Y, Leen AM, Sun J, Nakazawa Y, Yvon E, Heslop HE, Brenner MK, Rooney CM "." J. Immunother.. 2008 Sep;31(7):665-74. Pubmed PMID:
Hanley PJ, Cruz CR, Savoldo B, Leen AM, Stanojevic M, Khalil M, Decker W, Molldrem JJ, Liu H, Gee AP, Rooney CM, Heslop HE, Dotti G, Brenner MK, Shpall EJ, Bollard CM "." Blood. 2009 Aug 27;114(9):1958-67. Pubmed PMID:
Pule MA, Rousseau A, Vera J, Heslop HE, Brenner MK, Vanin EF "." Cytotherapy. 2008;10(5):526-39. Pubmed PMID:
Cela ME, Holladay MS, Rooney CM, Richardson S, Alexander B, Krance RA, Brenner MK, Heslop HE "." Bone Marrow Transplant.. 1996 Feb;17(2):243-7. Pubmed PMID:
Duncombe AS, Meager A, Prentice HG, Grundy JE, Heslop HE, Hoffbrand AV, Brenner MK "." Blood. 1990 Sep 1;76(5):1046-53. Pubmed PMID:
Brenner MK, Heslop HE, Rooney CM "." Vox Sang.. 1998;74:87-90. Pubmed PMID:
Brenner MK, Rill DR, Heslop HE, Rooney CM, Roberts WM, Li C, Nilson T, Krance RA "." Eur. J. Cancer. 1994;30(8):1171-6. Pubmed PMID:
Wagner HJ, Sili U, Gahn B, Vigouroux S, Huls MH, Xie W, Vignali D, Brenner MK, Heslop HE, Rooney CM "." Cytotherapy. 2003;5(3):231-40. Pubmed PMID:
Brenner MK, Rill DR, Moen RC, Krance RA, Heslop HE, Mirro J, Anderson WF, Ihle JN "." Ann. N. Y. Acad. Sci.. 1994 May 31;716:204-14; discuss. Pubmed PMID:
Brenner MK, Rill DR, Holladay MS, Heslop HE, Moen RC, Buschle M, Krance RA, Santana VM, Anderson WF, Ihle JN "." Lancet. 1993 Nov 6;342(8880):1134-7. Pubmed PMID:
Rousseau RF, Bollard CM, Heslop HE "." Expert Opin Biol Ther. 2001 Jul;1(4):663-74. Pubmed PMID:
Heslop HE "." Clin. Lab. Med.. 2000 Mar;20(1):183-95, x. Pubmed PMID:
Heslop HE "." Cytotherapy. 2007;9(6):519-20. Pubmed PMID:
Brenner MK, Heslop HE, Rill D, Li C, Nilson T, Roberts M, Smith C, Krance R, Rooney C "." Cold Spring Harb. Symp. Quant. Biol.. 1994;59:691-7. Pubmed PMID:
Heslop HE, Roskrow M "." Curr. Opin. Hematol.. 1995 Nov;2(6):417-22. Pubmed PMID:
Brenner MK, Cunningham JM, Sorrentino BP, Heslop HE "." Br. Med. Bull.. 1995 Jan;51(1):167-91. Pubmed PMID:
Heslop HE, Rooney CM, Brenner MK "." Blood Rev.. 1995 Dec;9(4):220-5. Pubmed PMID:
Bollard CM, Heslop HE, Brenner MK "." Int. J. Hematol.. 2001 Jan;73(1):14-22. Pubmed PMID:
Gottschalk S, Edwards OL, Sili U, Huls MH, Goltsova T, Davis AR, Heslop HE, Rooney CM "." Blood. 2003 Mar 1;101(5):1905-12. Pubmed PMID:
Savoldo B, Goss J, Liu Z, Huls MH, Doster S, Gee AP, Brenner MK, Heslop HE, Rooney CM "." Transplantation. 2001 Sep 27;72(6):1078-86. Pubmed PMID:
Savoldo B, Cubbage ML, Durett AG, Goss J, Huls MH, Liu Z, Teresita L, Gee AP, Ling PD, Brenner MK, Heslop HE, Rooney CM "." J. Immunol.. 2002 Jan 15;168(2):909-18. Pubmed PMID:
De Angelis B, Dotti G, Quintarelli C, Huye LE, Zhang L, Zhang M, Pane F, Heslop HE, Brenner MK, Rooney CM, Savoldo B "." Blood. 2009 Nov 26;114(23):4784-91. Pubmed PMID:
Ghazi A, Ashoori A, Hanley PJ, Brawley VS, Shaffer DR, Kew Y, Powell SZ, Grossman R, Grada Z, Scheurer ME, Hegde M, Leen AM, Bollard CM, Rooney CM, Heslop HE, Gottschalk S, Ahmed N "." J. Immunother.. 2012 Feb;35(2):159-68. Pubmed PMID:
Vera JF, Hoyos V, Savoldo B, Quintarelli C, Giordano Attianese GM, Leen AM, Liu H, Foster AE, Heslop HE, Rooney CM, Brenner MK, Dotti G "." Mol. Ther.. 2009 May;17(5):880-8. Pubmed PMID:
Bonini C, Brenner MK, Heslop HE, Morgan RA "." Biol. Blood Marrow Transplant.. 2011 Jan;17(1):S15-20. Pubmed PMID:
Pule M, Bollard CM, Heslop HE "." Curr. Opin. Mol. Ther.. 2002 Oct;4(5):467-75. Pubmed PMID:
Heslop H "." Clin. Cancer Res.. 2011 Jul 1;17(13):4189-91. Pubmed PMID:
Brenner MK, Heslop HE "." Baillieres Clin. Haematol.. 1991 Jul;4(3):727-49. Pubmed PMID:
Brenner MK, Heslop HE "." Curr. Opin. Immunol.. 1991 Oct;3(5):752-7. Pubmed PMID:
Rodriguez V, Kuehnle I, Heslop HE, Khan S, Krance RA "." Bone Marrow Transplant.. 2002 Mar;29(6):515-7. Pubmed PMID:
Horwitz EM, Horowitz MM, Difronzo NL, Kohn DB, Heslop HE "." Biol. Blood Marrow Transplant.. 2011 Feb;17(2):192-6. Pubmed PMID:
Popat U, Carrum G, Heslop HE "." Cancer Treat. Rev.. 2003 Feb;29(1):41343. Pubmed PMID:
Heslop HE "." Br. J. Haematol.. 1999 Apr;105(1):41311. Pubmed PMID:
Krance RA, Kuehnle I, Rill DR, Mei Z, Pinetta C, Evans W, Brown MP, Pulé M, Heslop HE, Brenner MK "." Biol. Blood Marrow Transplant.. 2003 Apr;9(4):273-81. Pubmed PMID:
Appel SH, Engelhardt JI, Henkel JS, Siklos L, Beers DR, Yen AA, Simpson EP, Luo Y, Carrum G, Heslop HE, Brenner MK, Popat U "." Neurology. 2008 Oct 21;71(17):1326-34. Pubmed PMID:
Hale GA, Bowman LC, Rochester RJ, Benaim E, Heslop HE, Krance RA, Horwitz EM, Cunningham JM, Tong X, Srivastava DK, Handgretinger R, Jones DP "." Biol. Blood Marrow Transplant.. 2005 Nov;11(11):912-20. Pubmed PMID:
Hale GA, Rochester RJ, Heslop HE, Krance RA, Gingrich JR, Benaim E, Horwitz EM, Cunningham JM, Tong X, Srivastava DK, Leung WH, Woodard P, Bowman LC, Handgretinger R "." Biol. Blood Marrow Transplant.. 2003 Nov;9(11):698-705. Pubmed PMID:
Kauffman WM, Heslop HE, Gronemeyer SA, Chen G, Krance RA "." Clin Radiol. 1997 Dec;52(12):903-6. Pubmed PMID:
Ahmed N, Salsman VS, Kew Y, Shaffer D, Powell S, Zhang YJ, Grossman RG, Heslop HE, Gottschalk S "." Clin. Cancer Res.. 2010 Jan 15;16(2):474-85. Pubmed PMID:
Quintarelli C, Dotti G, Hasan ST, De Angelis B, Hoyos V, Errichiello S, Mims M, Luciano L, Shafer J, Leen AM, Heslop HE, Rooney CM, Pane F, Brenner MK, Savoldo B "." Blood. 2011 Mar 24;117(12):3353-62. Pubmed PMID:
Bello-Fernandez C, Bird C, Heslop HE, Gottlieb DJ, Reittie JE, Rill DM, Holland M, Prentice HG, Brenner MK "." Blood. 1991 Mar 15;77(6):1283-9. Pubmed PMID:
Heslop HE "." Blood. 2009 Nov 5;114(19):4002-8. Pubmed PMID:
Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, "." Hum. Gene Ther.. 1996 Aug 20;7(13):1621-47. Pubmed PMID:
Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, "." Hum. Gene Ther.. 1996 Dec 1;7(18):2287-313. Pubmed PMID:
Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, "." Hum. Gene Ther.. 1997 Dec 10;8(18):2301-38. Pubmed PMID:
Vu T, Carrum G, Hutton G, Heslop HE, Brenner MK, Kamble R "." Bone Marrow Transplant.. 2007 Jun;39(11):705-9. Pubmed PMID:
Ramos CA, Narala N, Vyas GM, Leen AM, Gerdemann U, Sturgis EM, Anderson ML, Savoldo B, Heslop HE, Brenner MK, Rooney CM "." J. Immunother.. 2013 Jan;36(1):66-76. Pubmed PMID:
Heslop H, Richards AM, Nicholls MG, Espiner EA, Ikram H, Maslowski AH "." N. Z. Med. J.. 1985 Sep 11;98(786):739-42. Pubmed PMID:
Leen AM, Christin A, Khalil M, Weiss H, Gee AP, Brenner MK, Heslop HE, Rooney CM, Bollard CM "." J. Virol.. 2008 Jan;82(1):546-54. Pubmed PMID:
Voo KS, Fu T, Heslop HE, Brenner MK, Rooney CM, Wang RF "." Cancer Res.. 2002 Dec 15;62(24):7195-9. Pubmed PMID:
Gottlieb DJ, Prentice HG, Heslop HE, Bello C, Brenner MK "." Clin. Exp. Immunol.. 1992 Mar;87(3):493-8. Pubmed PMID:
Heslop HE, Bollard CM, Gottschalk S, Kuehnle I, Huls MH, Gee AP, Brenner MK, Rooney CM "." Cytotherapy. 2002;4(5):433-4. Pubmed PMID:
Gerdemann U, Keukens L, Keirnan JM, Katari UL, Nguyen CT, de Pagter AP, Ramos CA, Kennedy-Nasser A, Gottschalk SM, Heslop HE, Brenner MK, Rooney CM, Leen AM "." Blood. 2013 Jan 3;121(1):207-18. Pubmed PMID:
Straathof KC, Bollard CM, Rooney CM, Heslop HE "." Oncologist. 2003;8(1):83-98. Pubmed PMID:
Rooney CM, Roskrow MA, Smith CA, Brenner MK, Heslop HE "." J. Natl. Cancer Inst. Monographs. 1998;(23):89-93. Pubmed PMID:
Rooney CM, Bollard C, Huls MH, Gahn B, Gottschalk S, Wagner HJ, Anderson R, Prentice HG, Brenner MK, Heslop HE "." Ann. Hematol.. 2002;81:S39-42. Pubmed PMID:
Ahmed N, Salsman VS, Yvon E, Louis CU, Perlaky L, Wels WS, Dishop MK, Kleinerman EE, Pule M, Rooney CM, Heslop HE, Gottschalk S "." Mol. Ther.. 2009 Oct;17(10):1779-87. Pubmed PMID:
Straathof KC, Savoldo B, Heslop HE, Rooney CM "." Br. J. Haematol.. 2002 Sep;118(3):728-40. Pubmed PMID:
Heslop HE, Stevenson FK, Molldrem JJ "." Hematology Am Soc Hematol Educ Program. 2003;331-49. Pubmed PMID:
Rousseau RF, Biagi E, Dutour A, Yvon ES, Brown MP, Lin T, Mei Z, Grilley B, Popek E, Heslop HE, Gee AP, Krance RA, Popat U, Carrum G, Margolin JF, Brenner MK "." Blood. 2006 Feb 15;107(4):1332-41. Pubmed PMID:
Brenner MK, Heslop HE "." Leukemia. 1992;6:76-9. Pubmed PMID:
Bollard CM, Cooper LJ, Heslop HE "." Best Pract Res Clin Haematol. 2008 Sep;21(3):405-20. Pubmed PMID:
Gahn B, Hunt G, Rooney CM, Heslop HE "." Semin. Hematol.. 2002 Jan;39(1):41-7. Pubmed PMID:
Gajewski JL, LeMaistre CF, Silver SM, Lill MC, Selby GB, Horowitz MM, Rizzo JD, Heslop HE, Anasetti C, Maziarz RT "." Biol. Blood Marrow Transplant.. 2009 Dec;15(12):1493-501. Pubmed PMID:
Cruz CR, Gerdemann U, Leen AM, Shafer JA, Ku S, Tzou B, Horton TM, Sheehan A, Copeland A, Younes A, Rooney CM, Heslop HE, Bollard CM "." Clin. Cancer Res.. 2011 Nov 15;17(22):7058-66. Pubmed PMID:
Heslop HE, Price GM, Prentice HG, Cordingley FT, Webster AD, Hoffbrand AV, Brenner MK "." J. Immunol.. 1988 May 15;140(10):3461-6. Pubmed PMID:
Bollard CM, Gottschalk S, Huls MH, Molldrem J, Przepiorka D, Rooney CM, Heslop HE "." Leuk. Lymphoma. 2006 May;47(5):837-42. Pubmed PMID:
Heslop HE, Gottlieb DJ, Bianchi AC, Meager A, Prentice HG, Mehta AB, Hoffbrand AV, Brenner MK "." Blood. 1989 Sep;74(4):1374-80. Pubmed PMID:
Hutchings M, Moriwaki K, Dilloo D, Hoffmann T, Kimbrough S, Johnsen HE, Brenner MK, Heslop HE "." J Hematother. 1998 Jun;7(3):217-24. Pubmed PMID:
Tey SK, Dotti G, Rooney CM, Heslop HE, Brenner MK "." Biol. Blood Marrow Transplant.. 2007 Aug;13(8):913-24. Pubmed PMID:
Rooney CM, Smith CA, Ng CY, Loftin SK, Sixbey JW, Gan Y, Srivastava DK, Bowman LC, Krance RA, Brenner MK, Heslop HE "." Blood. 1998 Sep 1;92(5):1549-55. Pubmed PMID:
Sandlund JT, Bowman L, Heslop HE, Krance R, Mahmoud H, Pui CH, Hale G, Benaim E "." Cytotherapy. 2002;4(3):253-8. Pubmed PMID:
Perna SK, De Angelis B, Pagliara D, Hasan ST, Zhang L, Mahendravada A, Heslop HE, Brenner MK, Rooney CM, Dotti G, Savoldo B "." Clin. Cancer Res.. 2013 Jan 1;19(1):106-17. Pubmed PMID:
Heslop HE, Duncombe AS, Reittie JE, Bello-Fernandez C, Gottlieb DJ, Prentice HG, Mehta AB, Hoffbrand AV, Brenner MK "." Br. J. Haematol.. 1991 Feb;77(2):237-44. Pubmed PMID:
Carter BA, Karpen SJ, Quiros-Tejeira RE, Chang IF, Clark BS, Demmler GJ, Heslop HE, Scott JD, Seu P, Goss JA "." Transplantation. 2002 Oct 15;74(7):1050-2. Pubmed PMID:
Brenner MK, Heslop HE "." Cytotherapy. 2003;5(3):190-3. Pubmed PMID:
Heslop HE, Duncombe AS, Reittie JE, Bello-Fernandez C, Gottlieb DJ, Prentice HG, Hoffbrand AV, Brenner MK "." Transplant. Proc.. 1991 Feb;23(1):1704-5. Pubmed PMID:
Sili U, Huls MH, Davis AR, Gottschalk S, Brenner MK, Heslop HE, Rooney CM "." J. Immunother..;26(3):241-56. Pubmed PMID:
Heslop HE, Ng CY, Li C, Smith CA, Loftin SK, Krance RA, Brenner MK, Rooney CM "." Nat. Med.. 1996 May;2(5):551-5. Pubmed PMID:
Katzav S, Cleveland JL, Heslop HE, Pulido D "." Mol. Cell. Biol.. 1991 Apr;11(4):1912-20. Pubmed PMID:
Aguilar LK, Rooney CM, Heslop HE "." Curr Opin Oncol. 1999 Mar;11(2):96-101. Pubmed PMID:
Gottlieb DJ, Prentice HG, Mehta AB, Galazka AR, Heslop HE, Hoffbrand AV, Brenner MK "." Br. J. Haematol.. 1990 Aug;75(4):499-505. Pubmed PMID:
Comoli P, Dilloo D, Hutchings M, Hoffma T, Heslop HE "." Nat. Med.. 1996 Dec;2(12):1280-1. Pubmed PMID:
Leen AM, Myers GD, Sili U, Huls MH, Weiss H, Leung KS, Carrum G, Krance RA, Chang CC, Molldrem JJ, Gee AP, Brenner MK, Heslop HE, Rooney CM, Bollard CM "." Nat. Med.. 2006 Oct;12(10):1160-6. Pubmed PMID:
Fernandez Vina M, Heslop HE, Barker JN "." Biol. Blood Marrow Transplant.. 2013 Jan;19(1):S91-6. Pubmed PMID:
Gerdemann U, Christin AS, Vera JF, Ramos CA, Fujita Y, Liu H, Dilloo D, Heslop HE, Brenner MK, Rooney CM, Leen AM "." Mol. Ther.. 2009 Sep;17(9):1616-25. Pubmed PMID:
Heslop HE, Gottschalk SM, Bollard CM, Straathof KC, Huls MH, Brenner MK, Rooney CM "." Vox Sang.. 2004 Jul;87:230-4. Pubmed PMID:
Shafer JA, Heslop HE, Brenner MK, Carrum G, Wu MF, Liu H, Ahmed N, Gottschalk S, Kamble R, Leung KS, Myers GD, Bollard CM, Krance RA "." Leuk. Lymphoma. 2010 Apr;51(4):664-70. Pubmed PMID:
Popat U, Heslop HE, Durett A, May R, Krance RA, Brenner MK, Carrum G "." Bone Marrow Transplant.. 2006 Mar;37(6):547-52. Pubmed PMID:
Hongeng S, Krance RA, Bowman LC, Srivastava DK, Cunningham JM, Horwitz EM, Brenner MK, Heslop HE "." Lancet. 1997 Sep 13;350(9080):767-71. Pubmed PMID:
Cairo MS, Heslop H "." Bone Marrow Transplant.. 2008 Jan;41(2):97. Pubmed PMID:
Heslop HE "." Blood. 2013 May 2;121(18):3544-5. Pubmed PMID:
Brenner MK, Heslop H, Krance R, Horowitz M, Strother D, Nuchtern J, Grilley B, Martingano E, Cooper K "." Hum. Gene Ther.. 2000 Jul 1;11(10):1477-88. Pubmed PMID:
Engels EA, Savoldo B, Pfeiffer RM, Costello R, Zingone A, Heslop HE, Landgren O "." Transplantation. 2013 Feb 15;95(3):519-26. Pubmed PMID:
Kauffman WM, Zuckerman SL, Heslop HE, Krance RA "." J Ultrasound Med. 1995 Nov;14(11):877-9. Pubmed PMID:
Heslop HE, Brenner MK, Ganeshaguru K, Hoffbrand AV "." Br. J. Haematol.. 1991 Oct;79:14-6. Pubmed PMID:
Gottschalk S, Rooney CM, Heslop HE "." Annu. Rev. Med.. 2005;56:29-44. Pubmed PMID:
Kamdar KY, Rooney CM, Heslop HE "." Curr Opin Organ Transplant. 2011 Jun;16(3):274-80. Pubmed PMID:
Oblakowski P, Bello-Fernandez C, Reittie JE, Heslop HE, Galatowicz G, Veys P, Wilkes S, Prentice HG, Hazlehurst G, Hoffbrand AV "." Blood. 1991 May 1;77(9):1996-2001. Pubmed PMID:
Schriber JR, Anasetti C, Heslop HE, Leahigh AK "." Biol. Blood Marrow Transplant.. 2010 May;16(5):595-7. Pubmed PMID:
Heslop HE "." J. Immunother..;24(4):283-4. Pubmed PMID:
Smith CA, Ng CY, Heslop HE, Holladay MS, Richardson S, Turner EV, Loftin SK, Li C, Brenner MK, Rooney CM "." J Hematother. 1995 Apr;4(2):73-9. Pubmed PMID:
Sili U, Leen AM, Vera JF, Gee AP, Huls H, Heslop HE, Bollard CM, Rooney CM "." Cytotherapy. 2012 Jan;14(1):41466. Pubmed PMID:
Wagner HJ, Cheng YC, Huls MH, Gee AP, Kuehnle I, Krance RA, Brenner MK, Rooney CM, Heslop HE "." Blood. 2004 May 15;103(10):3979-81. Pubmed PMID:
Phipps S, Brenner M, Heslop H, Krance R, Jayawardene D, Mulhern R "." Bone Marrow Transplant.. 1995 Jun;15(6):829-35. Pubmed PMID:
Lee TC, Goss JA, Rooney CM, Heslop HE, Barshes NR, Caldwell YM, Gee AP, Scott JD, Savoldo B "." Clin Transplant.;20(6):689-94. Pubmed PMID:
Lee TC, Savoldo B, Rooney CM, Heslop HE, Gee AP, Caldwell Y, Barshes NR, Scott JD, Bristow LJ, O'Mahony CA, Goss JA "." Am. J. Transplant.. 2005 Sep;5(9):2222-8. Pubmed PMID:
Gerdemann U, Keirnan JM, Katari UL, Yanagisawa R, Christin AS, Huye LE, Perna SK, Ennamuri S, Gottschalk S, Brenner MK, Heslop HE, Rooney CM, Leen AM "." Mol. Ther.. 2012 Aug;20(8):1622-32. Pubmed PMID:
Myers GD, Bollard CM, Wu MF, Weiss H, Rooney CM, Heslop HE, Leen AM "." Bone Marrow Transplant.. 2007 Jun;39(11):677-86. Pubmed PMID:
Ahmed N, Ratnayake M, Savoldo B, Perlaky L, Dotti G, Wels WS, Bhattacharjee MB, Gilbertson RJ, Shine HD, Weiss HL, Rooney CM, Heslop HE, Gottschalk S "." Cancer Res.. 2007 Jun 15;67(12):5957-64. Pubmed PMID:
Rencher SD, Hanif I, Heslop HE, Turner VE, Brenner MK, Hurwitz JL "." Bone Marrow Transplant.. 1992 Dec;10(6):521-7. Pubmed PMID:
Di Stasi A, De Angelis B, Rooney CM, Zhang L, Mahendravada A, Foster AE, Heslop HE, Brenner MK, Dotti G, Savoldo B "." Blood. 2009 Jun 18;113(25):6392-402. Pubmed PMID:
Vera J, Savoldo B, Vigouroux S, Biagi E, Pule M, Rossig C, Wu J, Heslop HE, Rooney CM, Brenner MK, Dotti G "." Blood. 2006 Dec 1;108(12):3890-7. Pubmed PMID:
Leen AM, Myers GD, Bollard CM, Huls MH, Sili U, Gee AP, Heslop HE, Rooney CM "." Ann. N. Y. Acad. Sci.. 2005 Dec;1062:104-15. Pubmed PMID:
Ahmed N, Heslop HE, Mackall CL "." Pediatr. Clin. North Am.. 2010 Feb;57(1):83-96. Pubmed PMID:
Heslop HE "." Blood. 2011 Sep 29;118(13):3452-3. Pubmed PMID:
Heslop HE, Brenner MK "." Mol. Ther.. 2008 Sep;16(9):1520-1. Pubmed PMID:
Lin YF, Lairson DR, Chan W, Du XL, Leung KS, Kennedy-Nasser AA, Martinez CA, Gottschalk SM, Bollard CM, Heslop HE, Brenner MK, Krance RA "." Biol. Blood Marrow Transplant.. 2010 Sep;16(9):1272-81. Pubmed PMID:
Bollard CM, Straathof KC, Huls MH, Leen A, Lacuesta K, Davis A, Gottschalk S, Brenner MK, Heslop HE, Rooney CM "." J. Immunother..;27(4):317-27. Pubmed PMID:
Browett PJ, Heslop HE, Mehta AB, Norton JD "." Acta Haematol.. 1990;83(4):203-5. Pubmed PMID:
Savoldo B, Heslop HE, Rooney CM "." Leuk. Lymphoma. 2000 Nov;39(41400):455-64. Pubmed PMID:
Heslop HE, Hoffbrand AV, Brenner MK "." Leukemia. 1993 Sep;7(9):1476. Pubmed PMID:
Heslop HE, Perez M, Benaim E, Rochester R, Brenner MK, Rooney CM "." J Clin Apher. 1999;14(3):154-6. Pubmed PMID:
Brenner MK, Heslop HE, Rill D, Li C, Smith C, Krance R, Rooney C "." Cytokines Mol Ther. 1996 Sep;2(3):193-200. Pubmed PMID:
Ganguly S, Carrum G, Nizzi F, Heslop HE, Popat U "." Am. J. Hematol.. 2004 Jan;75(1):48-51. Pubmed PMID:
Moriwaki K, Sutton RE, Perez M, Brenner MK, Heslop HE "." Cytotherapy. 1999;1(6):433-8. Pubmed PMID:
Kamble RT, Clark DA, Leong HN, Heslop HE, Brenner MK, Carrum G "." Bone Marrow Transplant.. 2007 Sep;40(6):563-6. Pubmed PMID:
Pakakasama S, Eames GM, Morriss MC, Huls MH, Rooney CM, Heslop HE, Krance RA "." Transplantation. 2004 Sep 15;78(5):755-7. Pubmed PMID:
Gottschalk S, Heslop HE, Roon CM "." Adv. Cancer Res.. 2002;84:175-201. Pubmed PMID:
Straathof KC, Bollard CM, Popat U, Huls MH, Lopez T, Morriss MC, Gresik MV, Gee AP, Russell HV, Brenner MK, Rooney CM, Heslop HE "." Blood. 2005 Mar 1;105(5):1898-904. Pubmed PMID:
Rooney CM, Roskrow MA, Suzuki N, Ng CY, Brenner MK, Heslop H "." Ann. Oncol.. 1998;9:S129-32. Pubmed PMID:
Savoldo B, Goss JA, Hammer MM, Zhang L, Lopez T, Gee AP, Lin YF, Quiros-Tejeira RE, Reinke P, Schubert S, Gottschalk S, Finegold MJ, Brenner MK, Rooney CM, Heslop HE "." Blood. 2006 Nov 1;108(9):2942-9. Pubmed PMID:
Deeg HJ, Blazar BR, Bolwell BJ, Long GD, Schuening F, Cunningham J, Rifkin RM, Abhyankar S, Briggs AD, Burt R, Lipani J, Roskos LK, White JM, Havrilla N, Schwab G, Heslop HE "." Blood. 2001 Oct 1;98(7):2052-8. Pubmed PMID:
Duncombe AS, Heslop HE, Turner M, Meager A, Priest R, Exley T, Brenner MK "." J. Immunol.. 1989 Dec 1;143(11):3828-34. Pubmed PMID:
Cordingley FT, Bianchi A, Hoffbrand AV, Reittie JE, Heslop HE, Vyakarnam A, Turner M, Meager A, Brenner MK "." Lancet. 1988 Apr 30;1(8592):969-71. Pubmed PMID:
Koehler M, Hurwitz CA, Krance RA, Coustan-Smith E, Williams LL, Santana V, Ribeiro RC, Brenner MK, Heslop HE "." Bone Marrow Transplant.. 1994 May;13(5):571-5. Pubmed PMID:

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Funding

SPORE in Lymphoma - #P50 CA126752: $1,519,185.00 (09/01/2007 - 08/31/2027); The overall goal of the Lymphoma SPORE at �� and Houston Methodist Hospital is to devise in the laboratory, and validate in the clinic, interventional strategies, with the broad objective of improving outcome in lymphomas and in chronic lymphocytic leukemia (CLL).

Immunotherapy of Hematologic Malignancy: $1,250,000.00 (10/01/2018 - 09/30/2023); The major goals of this program are to develop immunotherapy approaches for a broad range of hematologic malignancies

Training in Cell and Gene Therapy - #T32 HL092332: $276,642.00 (07/01/2003 - 06/30/2028); This is a training grant for graduate students and postdoctoral fellows in Cell and Gene Therapy.

Blood and Marrow Transplant Clinical Trials Network (BMT CTN) - Core Clinical Centers (U01) - #U10 HL10894: $100,000.00 (08/08/2011 - 06/30/2031)

Meg Vosburg T cell Lymphoma Dream Team: $8,000,000.00 (03/01/2019 - 10/01/2023)

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Helen E Heslop

Helen E Heslop, MD, DSc (Hon)

Helen E Heslop, MD, DSc (Hon)

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832-824-4662