Geoffrey A. Preidis, M.D., Ph.D.
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Geoffrey A. Preidis, M.D., Ph.D.
Associate Professor
Positions
- Associate Professor
-
Department of Pediatrics
Division of Gastroenterology, Hepatology & Nutrition
²ÝÁñÉçÇøÈë¿Ú and Texas Children's Hospital
Houston, Texas United States
- Associate Director
-
Medical Scientist Training Program (M.D./Ph.D.)
- Faculty
-
Development, Disease Models & Therapeutics Graduate Program
- Faculty
-
Immunology & Microbiology Graduate Program
- Faculty
-
Clinical Scientist Training Graduate Program
Addresses
- Texas Children's Hospital (Hospital)
-
6701 Fannin Street
Houston, TX 77030
United States
Phone: (832) 822-3131
gapreidi@texaschildrens.org
- Pediatric Gastroenterology, Hepatology & Nutrition Research Laboratory (Office)
-
Texas Children's Hospital
Feigin Tower 860.24
Houston, TX 77030
United States
Phone: (832) 822-3617
Fax: (832) 825-4893
geoffrey.preidis@bcm.edu
- Pediatric Gastroenterology, Hepatology & Nutrition Research Laboratory (Lab)
-
Texas Children's Hospital
Feigin Tower 860.01
Houston, TX 77030
United States
Phone: (832) 822-3617
Fax: (832) 825-4893
gp147834@bcm.edu
Education
- Clinical Fellowship at ²ÝÁñÉçÇøÈë¿Ú & Texas Children's Hospital
- 06/2018 - Houston, Texas United States
- Pediatric Gastroenterology, Hepatology & Nutrition
- Residency at ²ÝÁñÉçÇøÈë¿Ú & Texas Children's Hospital
- 06/2014 - Houston, Texas United States
- Pediatrics
- Internship at ²ÝÁñÉçÇøÈë¿Ú & Texas Children's Hospital
- 06/2013 - Houston, Texas United States
- Pediatrics
- MD from Baylor College Of Medicine
- 05/2012 - Houston, Texas United States
- PhD from ²ÝÁñÉçÇøÈë¿Ú
- 02/2011 - Houston, Texas United States
- Translational Biology and Molecular Medicine
- AB from Harvard University
- 06/2003 - Cambridge, Massachusetts United States
- Physics, cum laude
Certifications
- Medical License
- Texas Medical Board
- Board Certification - General Pediatrics
- American Board of Pediatrics
- Board Certification - Pediatric Gastroenterology
- American Board of Pediatrics
Professional Interests
- Neonatal Gastroenterology, Hepatology & Nutrition
- Sex Differences in Nutritional Physiology
- Gut Microbiome and Probiotics
- Neurogastroenterology and Motility
- Liver and Intestinal Physiology
- Undernutrition
- Bile Acids
- Nuclear Hormone Receptors
- Postnatal Growth Failure
Professional Statement
Our goal is to define mechanisms through which early life undernutrition alters metabolism and to determine how undernutrition influences intestinal and liver function. Undernutrition causes acute medical problems, but also long term health problems that may result from permanent epigenetic changes that alter transcription or via changes in the gut microbiome. Current studies focus on how malnutrition alters hepatic secretion, transcriptional programming, gastrointestinal motility, and host-microbiome interactions to impact growth. Our work is pertinent to those suffering from nutritional deficiencies caused by a wide range of medical and socioeconomic factors, including preterm and underweight newborns in the neonatal intensive care unit, adolescents with anorexia nervosa, and children with severe acute malnutrition in the developing world.Websites
Selected Publications
- Tessier MEM, Shneider BL, Petrosino JF, Preidis GA. "." J Pediatr Gastroenterol Nutr. 2025;in press
- Preidis GA. "." Gut Microbes. 2025;17:2457499. Pubmed PMID:
- Preidis GA, Berrington JE. "." Nat Rev Gastroenterol Hepatol. 2025;22:5-6. Pubmed PMID:
- Britton RA, Verdu EF, Di Rienzi SC, Reyes Munoz A, Tarr PI, Preidis GA. "." Gastroenterology. 2024;167:1059-1064. Pubmed PMID:
- Dike PN, Soni KG, Chang DS, Preidis GA. "." FASEB Bioadv. 2024;6:200-206. Pubmed PMID:
- Chang DS, Soni KG, Preidis GA. "." Front Neurol. 2024;15:334319. Pubmed PMID:
- Patel H, Harris RA, Qian JH, Oezguen N, Watson A, Szigeti RG, Cho S, Ruan W, Britto S, Opekun A, Preidis G, Kellermayer R. "." Cell Mol Gastroenterol Hepatol. 2024;17:1069-1071. Pubmed PMID:
- Adeniyi-Ipadeola GO, Hoffman KL, Yang H, Javornik Cregeen SJ, Preidis GA, Ramani S, Hair AB. "." Pediatr Res. 2024;95:1564-1571. Pubmed PMID:
- McFarland LV, Hecht G, Sanders ME, Goff DA, Goldstein EJC, Hill C, Johnson S, Kashi MR, Kullar R, Marco ML, Merenstein DJ, Millette M, Preidis GA, Quigley EMM, Reid G, Salminen S, Sniffen JC, Sokol H, Szajewska H, Tancredi DJ, Woolard K. "." JAMA Netw Open. 2023;6:e2346872. Pubmed PMID:
- Edwards PT, Soni KG, Conner ME, Fowler SW, Foong JPP, Stavely R, Cheng LS, Preidis GA. "." Neurogastroenterol Motil. 2023;35:e14676. Pubmed PMID:
- Preidis GA. "." Manson's Tropical Diseases, 24th Edition. Farrar J, Garcia PJ, Hotez PJ, Junghanss T, Kang G, Lalloo D, White NJ, Eds. 2023;1161-1177.
- Shane AL, Preidis GA. "." JAMA Pediatr. 2023;177(9):879-880. Pubmed PMID:
- Neves LL, Hair AB, Preidis GA. "." Gut Microbes. 2023;15:2190301. Pubmed PMID:
- Lynch LE, Hair AB, Soni KG, Yang H, Gollins LA, Narvaez-Rivas M, Setchell KDR, Preidis GA. "." Gut Microbes. 2023;15:2183690. Pubmed PMID:
- Merenstein D, Pot B, Leyer G, Ouwehand AC, Preidis GA, Elkins CA, Hill C, Lewis ZT, Shane AL, Zmora N, Petrova MI, Collado MC, Morelli L, Montoya GA, Szajewska H, Tancredi DJ, Sanders ME. "." Gut Microbes. 2023;15:2185034. Pubmed PMID:
- Holzapfel LF, Hair AB, Preidis GA, Halder T, Yang H, Unger JP, Freedman S, Martin, CR. "." J Pediatr Gastroenterol Nutr. 2023;76:206-212. Pubmed PMID:
- Preidis GA, Chumpitazi BP, Shulman RJ. "." In: Pediatric Neurogastroenterology. 2022;Springer Nature Switzerland AG(Faure C, Thapar N, Di Lorenzo C, Eds.):80-100.
- Preidis GA. "." J Pediatr Gastroenterol Nutr. 2022;75(4):387-388. Pubmed PMID:
- Suh JH, Kim KH, Conner ME, Moore DD, Preidis GA. "." Front Nutr. 2022;9:831879. Pubmed PMID:
- Patterson GT, Osorio EY, Peniche A, Dann SM, Cordova E, Preidis GA, Suh JH, Ito I, Saldarriaga OA, Loeffelholz M, Ajami NJ, Travi BL, Melby PC. "." Front Immunol. 2022;13:846155.
- Amato KR, Arrieta MC, Azad MB, Bailey MT, Broussard JL, Bruggeling CE, Claud EC, Costello EK, Davenport ER, Dutilh BE, Ewald HAS, Ewald P, Hanlon EC, Keshavarzian A, Maurice CF, Miller G, Preidis GA, Segurel L, Singer B, Subramanian S, Julion W, et al. "." Proc Natl Acad Sci USA. 2021;118:e2017947118. Pubmed PMID:
- Preidis GA, Su GL, Morgan RL. "." Gastroenterology. 2021;160:2633-5. Pubmed PMID:
- Preidis GA, Soni KG, Suh JH, Halder T, Kim KH, Choi JM, Li F, Devaraj S, Conner ME, Coarfa C, Jung SY, Moore DD. "." Hepatol Commun. 2020;4(12):1835-1850. Pubmed PMID:
- Soni KG, Dike PN, Suh JH, Halder T, Edwards PT, Foong JPP, Conner ME, Preidis GA. "." Neurogastroenterol Motil. 2020;32(12):e13936. Pubmed PMID:
- Edwards PT, Kashyap PC, Preidis GA. "." Am J Physiol Gastrointest Liver Physiol. 2020;319:G382-390. Pubmed PMID:
- Pammi M, Preidis GA, Tarnow-Mordi WO. "." Biochem Cell Biol. 2021;99:20-24. Pubmed PMID:
- Morgan RL, Preidis GA, Kashyap PC, Weizman AV, Sadeghirad B. "." Gastroenterology. 2020;159:467-480. Pubmed PMID:
- Preidis GA, Weizman AV, Kashyap PC, Morgan RL. "." Gastroenterology. 2020;159:708-738. Pubmed PMID:
- Su GL, Ko CW, Bercik P, Morgan RL, Weizman AV, Kashyap P, Preidis GA. "." Gastroenterology. 2020;159:707. Pubmed PMID:
- Soni KG, Halder T, Conner ME, Preidis GA. "." Neurogastroenterol Motil. 2019;31:e13654. Pubmed PMID:
- Ford SL, Lohmann P, Preidis GA, Gordon PS, O'Donnell A, Hagan J, Venkatachalam A, Balderas M, Luna RA, Hair AB. "." Am J Clin Nutr. 2019;109:1088-1097. Pubmed PMID:
- Shin A, Preidis GA, Shulman R, Kashyap PC. "." Clin Gastroenterol Hepatol. 2019;17:256-274. Pubmed PMID:
- Thaxton GE, Melby PC, Manary MJ, Preidis GA. "." Gastroenterol Clin North Am. 2018;47:813-827. Pubmed PMID:
- Alves da Silva AV, de Castro Oliveira SB, Di Rienzi SC, Brown-Steinke K, Dehan LM, Rood JK, Carreira VS, Le H, Maier EA, Betz KJ, Aihara E, Ley RE, Preidis GA, Shen L, Moore SR. "." Curr Dev Nutr. 2018;3:nzy070. Pubmed PMID:
- Preidis GA, Kim KH, Moore DD. "." J Clin Invest. 2017;127:1193-1201. Pubmed PMID:
- Velly H, Britton RA, Preidis GA. "." Gut Microbes. 2017;8:98-112. Pubmed PMID:
- Preidis GA, Chumpitazi BP, Shulman RJ. "." In: Pediatric Neurogastroenterology. 2017;Springer International Publishing, Switzerland(Faure C, Thapar N, Di Lorenzo C, Eds.):53-70.
- Preidis GA, Ajami NJ, Wong MC, Bessard BC, Conner ME, Petrosino JF. "." J Nutr. 2016;146:940-8. Pubmed PMID:
- Preidis GA, Chiou EH. "." In: The NASPGHAN Fellows’ Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition - Second Edition. 2017;NASPGHAN, Ambler, PA(Li BUK, Hurtado CW, Eds.):655-59.
- Preidis GA, Leung DH. "." In: The NASPGHAN Fellows’ Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition - Second Edition. 2017;NASPGHAN, Ambler, PA(Li BUK, Hurtado CW, Eds.):353-57.
- Preidis GA, Luna RA, Hollister EB, Schady D, Finegold MJ, Versalovic J, Shulman RJ. "." Therap Adv Gastroenterol. 2016;9(5):749-51. Pubmed PMID:
- Preidis GA, Ajami NJ, Wong MC, Bessard BC, Conner ME, Petrosino JF. "." J Nutr Biochem. 2015;26:1050-7. Pubmed PMID:
- Preidis GA, Hotez PJ. "." PLoS Negl Trop Dis. 2015;9:e0003382. Pubmed PMID:
- Ahmed S, Kim MH, Dave AC, Sabelli R, Kanjelo K, Preidis GA, Giordano TP, Chiao E, Hosseinipour M, Kazembe PN, Chimbwandira F, Abrams EJ. "." J Int AIDS Soc. 2015;18:19305. Pubmed PMID:
- LaCourse SM, Chester FM, Preidis G, McCrary LM, Maliwichi M, McCollum ED, Hosseinipour MC. "." J Trop Pediatr. 2015;61:44-53. Pubmed PMID:
- LaCourse SM, Chester FM, Preidis G, McCrary LM, Arscott-Mills T, Maliwichi M, James G, McCollum ED, Hosseinipour MC. "." Pediatr Infect Dis J. 2014;33:1200-2. Pubmed PMID:
- Finocchario-Kessler S, Gautney B, Khamadi S, Okoth V, Goggin K, Spinler J, Mwangi A, Kimanga D, Clark K, Olungae H, Preidis GA. "." AIDS. 2014;28:S313-21. Pubmed PMID:
- Perry SH, Swamy P, Preidis GA, Mwanyumba A, Motsa N, Sarero HN. "." AIDS. 2014;28:791-3. Pubmed PMID:
- Preidis GA, Keaton MA, Campeau P, Bessard BC, Conner ME, Hotez PG. "." J Nutr. 2014;144:273-81. Pubmed PMID:
- McCollum ED, Preidis GA, Maliwichi M, Olson D, McCrary M, Kazembe PN, van der Horst C, Hoffman I, Hosseinipour MC. "." J Acquir Immun Defic Syndr. 2014;66:223-30. Pubmed PMID:
- Bjornstad, E, Preidis GA, Lufesi N, Olson D, Kamthunzi P, Hosseinipour M, McCollum ED. "." Paediatr Int Child Health. 2014;34:29-36. Pubmed PMID:
- Olson D, Preidis GA, Milazi R, Spinler JK, Lufesi N, Mwansambo C, Hosseinipour MC, McCollum ED. "." Trop Med Int Health. 2013;18:879-86. Pubmed PMID:
- Kim MH, Ahmed S, Preidis GA, Abrams EJ, Hosseinipour MC, Giordano TP, Chiao EY, Paul ME, Bhalakia A, Nanthuru D, Kazembe PN. "." PLoS One. 2013;8:e64979. Pubmed PMID:
- Olson D, Davis NL, Milazi R, Miller W, Mwansambo C, Preidis GA, Hosseinipour MC, McCollum ED. "." Trop Med Int Health. 2013;18:871-8. Pubmed PMID:
- McCollum ED, Bjornstad E, Preidis GA, Hosseinipour MC, Lufesi N. "." Trans R Soc Trop Med Hyg. 2013;107:285-92. Pubmed PMID:
- Preidis GA, McCollum ED, Garbino A, Kamiyango W, Hosseinipour MC, Kazembe PN, Schutze GE, Kline MW. "." J Acquir Immune Defic Syndr. 2013;63:e16-22. Pubmed PMID:
- Kim MH, Ahmed S, Buck WC, Preidis GA, Hosseinipour MC, Bhalakia A, Nanthuru D, Kazembe PN, Chimbwandira F, Giordano TP, Chiao EY, Schutze GE, Kline MW. "." J Int AIDS Soc. 2012;15:1-11. Pubmed PMID:
- Preidis GA, Saulnier DM, Blutt SE, Mistretta TA, Riehle KP, Major AM, Venable SF, Barrish JP, Finegold MJ, Petrosino JF, Guerrant RL, Conner ME, Versalovic J. "." J Pediatr Gastroenterol Nutr. 2012;55:299-307. Pubmed PMID:
- Preidis GA, Saulnier DM, Blutt SE, Mistretta TA, Riehle KP, Major AM, Finegold MJ, Petrosino JF, Conner ME, Versalovic J. "." FASEB J. 2012;26:1960-9. Pubmed PMID:
- Preidis GA, McCollum ED, Mwansambo C, Kazembe PN, Schutze GE, Kline MW. "." J Pediatr. 2011;159:484-9. Pubmed PMID:
- McCollum ED, Preidis GA, Golitko C, Siwande LD, Mwansambo C, Kazembe PN, Hosseinipour MC, Schutze GE, Kline MW. "." Pediatr Infect Dis J. 2011;30:e75-81. Pubmed PMID:
- Thomas CM, Preidis GA, Versalovic J. "." Old Herborn University Seminars. 2011;24:83-94.
- Preidis GA, Hill C, Guerrant RL, Ramakrishna BS, Tannock GW, Versalovic J. "." Gastroenterology. 2011;140:8-14. Pubmed PMID:
- Preidis GA, Shapiro CD, Pierre I, Dyer MJ, Kozinetz CA, Grimes RM. "." J Health Care Poor Underserved. 2010;21:430-7. Pubmed PMID:
- McCollum ED, Preidis GA, Kabue MM, Singogo EBM, Mwansambo C, Kazembe PN, Kline MW. "." PLoS One. 2010;5:e9626. Pubmed PMID:
- Preidis GA, Versalovic J. "." Gastroenterology. 2009;136:2015-31. Pubmed PMID:
- Preidis GA, Huang HC, Lewis DE, Castellanos-Gonzalez A, Rogers KA, Ward HD, White AC. "." Am J Trop Med Hyg. 2007;77:583-5. Pubmed PMID:
- Popovich PG, van Rooijen N, Hickey WF, Preidis G, McGaughy V. "." Exp Neurol. 2003;182:275-87. Pubmed PMID:
Funding
- Advancing Clinical Science in Pediatric Gastroparesis - #U01 DK112194 (09/25/2016 - 07/31/2027) Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
- The Metabolic Basis for Impaired Bile Acid Synthesis in Malnutrition - #R01 DK133301 (07/15/2022 - 06/30/2027) Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
- Impaired Bile Acid Synthesis Due To CYP7A1 and CYP7B1 Suppression in Malnutrition - #R03 DK129495-01 (07/15/2021 - 06/30/2023) Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
- Nuclear Receptor Mediated Bile Acid Alterations and Coagulopathy in Protein-Energy Undernutrition - #K08 DK113114-01 (09/01/2017 - 08/31/2022) Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
- K08 Mentored Clinical Scientist Research Career Development Award
- Bile Acid and Metagenomic Profiles in Very Low Birthweight Preterm Neonates (05/06/2020 - 05/05/2022) Grant funding from Men of Distinction
- AGA-Rome Foundation Functional GI and Motility Disorders Pilot Award (07/01/2017 - 06/30/2018) Grant funding from American Gastroenterological Association / Rome Foundation
- Bile Acid Mediated Dysmotility in Protein-Energy Undernutrition
- Chao Physician-Scientist Award (07/01/2017 - 08/31/2017) Grant funding from Ting Tsung and Wei Fong Chao Foundation
- Nuclear Receptor Mediated Bile Acid Alterations and Coagulopathy in Protein-Energy Undernutrition
- ANMS Research Grant (01/01/2017 - 06/30/2017) Grant funding from American Neurogastroenterology and Motility Society
- Bile Acids and Intestinal Dysmotility in Early-Life Undernutrition
- Functional and Mechanistic Award (11/01/2016 - 06/30/2017) Grant funding from The Alkek Center for Metagenomics and Microbiome Research
- Microbial Mechanisms of Pathogenesis Underlying non-Helicobacter Gastritis
- Pilot/Feasibility Award (02/06/2016 - 02/05/2018) Grant funding from The Texas Medical Center Digestive Disease Center
- Persistent Epigenetic and Metabolic Consequences of Early Undernutrition.
- NASPGHAN Foundation / Nestle Nutrition Research Young Investigator Development Award (11/15/2015 - 11/14/2017) Grant funding from North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition
- Glycan metabolism shapes the undernourished intestinal microbiome and influences weight gain
- Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) - #5T32DK007664 (07/01/2015 - 08/31/2017) Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
- Mechanisms of Dysregulation of Bile Acid Synthesis in Protein-Energy Undernutrition
- Early Career Award (10/01/2013 - 09/30/2014) Grant funding from Thrasher Research Fund
- The Intestinal Microbiome as a Biomarker and Therapeutic Target in Severe Acute Malnutrition
- Young Investigator Grant for Probiotics Research (07/01/2013 - 06/30/2014) Grant funding from Global Probiotics Council
- Elucidating the Role of the Intestinal Microbiome in Protein-Energy Undernutrition
- Ruth L. Kirschstein National Research Service Award for Individual Predoctoral M.D./Ph.D. Fellows (F30) - #5F30DK081269 (06/01/2009 - 05/30/2012) Grant funding from National Institute of Diabetes and Digestive and Kidney Diseases
- Mechanisms of Immunomodulation by Probiotic L. reuteri in Acute Gastroenteritis
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