David J Durgan, Ph.D.
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David J Durgan, Ph.D.
Assistant Professor
Positions
- Assistant Professor
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Integrative Physiology & Anesthesiology
草榴社区入口
Houston, TX US
Addresses
- BCM-315B (Office)
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Houston, TX 77030
United States
- BCM 307/315B (Lab)
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Houston, TX 77030
United States
Education
- PhD from University of Alabama at Birmingham
- 12/2011 - Birmingham, AL
- MS from California Polytechnic State University
- 03/2005 - San Luis Obispo, CA
- BS from University of Wyoming
- 06/2000 - Laramie, WY
Professional Interests
- Role of the gut microbiota in cardiovascular disease
Professional Statement
Ongoing research in my laboratory is focused on the role of the gut microbiota in cardiovascular diseases. We are particularly interested in how these bacteria residing in the gut influence host blood pressure. We have shown that disrupting the bacterial population in the gut leads to hypertension, and that various methods to normalize gut bacteria can be therapeutic. Using rodent models, in vitro assay, and muli-omics approaches we are working to understand the mechanisms of communication between the gut microbiota and host that are involved in blood pressure regulation.Websites
Selected Publications
- Shi H, Zhang B, Abo-Hamzy T, Nelson JW, Ambati CSR, Petrosino JF, Bryan RM Jr, Durgan DJ. "." Circ Res. 2021; Pubmed PMID:
- Nelson JW, Phillips SC, Ganesh BP, Petrosino JF, Durgan DJ, Bryan RM "." FASEB J. 2021 Feb; Pubmed PMID:
- Durgan DJ, Lee J, McCullough LD, Bryan RM Jr. "." Stroke. 2019 Aug; Pubmed PMID:
- Ganesh BP, Nelson JW, Eskew JR, Ganesan A, Ajami NJ, Petrosino JF, Bryan RM Jr, Durgan DJ. "." Hypertension. 2018 Nov; Pubmed PMID:
- Durgan DJ "." Hypertens Rep.. 2017; Pubmed PMID:
- Adnan,S.;Nelson,J.W.;Ajami,N.J.;Venna,V.R.;Petrosino,J.F.;Bryan,R.M.,Jr;Durgan,D.J.; "." Physiol Genomics.. 2016; Pubmed PMID:
- Durgan DJ, Ganesh BP, Cope JL, Ajami NJ, Phillips SC, Petrosino JF, Hollister EB, Bryan RM "." Hypertension. 2016; Pubmed PMID:
- Durgan DJ, Crossland RF, Bryan RM. "." J Cereb Blood Flow Metab.. 2016; Pubmed PMID:
- Lloyd EE, Durgan DJ, Martini SR, Bryan RM. "." Hypertension. 2015; Pubmed PMID:
- Durgan DJ, Crossland RF, Lloyd EE, Phillips SC, Bryan RM. "." J Cereb Blood Flow Metab. 2015; Pubmed PMID:
- Crossland RF, Durgan DJ, Lloyd EE, Phillips SC, Reddy AK, Marrelli SP, Bryan RM. "." Am J Physiol Regul Integr Comp Physiol.. 2013; Pubmed PMID:
- Durgan DJ, Bryan RM "." J Am Heart Assoc.. 2012; Pubmed PMID:
- Durgan DJ, Pat BM, Laczy B, Bradley JA, Tsai JY, Grenett MH, Ratcliffe WF, Brewer RA, Nagendran J, Villegas-Montoya C, Zou C, Zou L, Johnson RL, Dyck JR, Bray MS, Gamble KL, Chatham JC, Young ME. "." J Biol Chem.. 2011; Pubmed PMID:
- Durgan DJ, Tsai JY, Grenett MH, Pat BM, Ratcliffe WF, Villegas-Montoya C, Garvey ME, Nagendran J, Dyck JR, Bray MS, Gamble KL, Gimble JM, Young ME "." Chronobiol Int.. 2011; Pubmed PMID:
- Durgan DJ, Young ME "." Circ Res.. 2010; Pubmed PMID:
- Durgan DJ, Pulinilkunnil T, Villegas-Montoya C, Garvey ME, Frangogiannis NG, Michael LH, Chow CW, Dyck JR, Young ME "." Circ Res.. 2010; Pubmed PMID:
- Tsai JY, Kienesberger PC, Pulinilkunnil T, Sailors MH, Durgan DJ, Villegas-Montoya C, Jahoor A, Gonzalez R, Garvey ME, Boland B, Blasier Z, McElfresh TA, Nannegari V, Chow CW, Heird WC, Chandler MP, Dyck JR, Bray MS, Young ME. "." J Biol Chem.. 2010; Pubmed PMID:
- Lockridge JB, Sailors ML, Durgan DJ, Egbejimi O, Jeong WJ, Bray MS, Stanley WC, Young ME. "." J Lipid Res.. 2008; Pubmed PMID:
- Durgan DJ, Young ME. "." Cardiovasc Drugs Ther.. 2008; Pubmed PMID:
- Bray MS, Shaw CA, Moore MW, Garcia RA, Zanquetta MM, Durgan DJ, Jeong WJ, Tsai JY, Bugger H, Zhang D, Rohrwasser A, Rennison JH, Dyck JR, Litwin SE, Hardin PE, Chow CW, Chandler MP, Abel ED, Young ME "." Am J Physiol Heart Circ Physiol.. 2008; Pubmed PMID:
- Kung TA, Egbejimi O, Cui J, Ha NP, Durgan DJ, Essop MF, Bray MS, Shaw CA, Hardin PE, Stanley WC, Young ME. "." J Mol Cell Cardiol.. 2007; Pubmed PMID:
- Durgan DJ, Moore MW, Ha NP, Egbejimi O, Fields A, Mbawuike U, Egbejimi A, Shaw CA, Bray MS, Nannegari V, Hickson-Bick DL, Heird WC, Dyck JR, Chandler MP, Young ME. "." Am J Physiol Heart Circ Physiol.. 2007; Pubmed PMID:
- Durgan DJ, Trexler NA, Egbejimi O, McElfresh TA, Suk HY, Petterson LE, Shaw CA, Hardin PE, Bray MS, Chandler MP, Chow CW, Young ME "." J Biol Chem.. 2006; Pubmed PMID:
- Durgan DJ, Smith JK, Hotze MA, Egbejimi O, Cuthbert KD, Zaha VG, Dyck JR, Abel ED, Young ME. "." Am J Physiol Heart Circ Physiol.. 2006; Pubmed PMID:
- Durgan DJ, Hotze MA, Tomlin TM, Egbejimi O, Graveleau C, Abel ED, Shaw CA, Bray MS, Hardin PE, Young ME. "." Am J Physiol Heart Circ Physiol.. 2005; Pubmed PMID:
Memberships
- American Heart Association
- American Physiological Society
- Texas Medical Center Digestive Disease Center
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