Cintia S De Paiva, M.D., Ph.D.
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Positions
- Professor, Caroline Elles Endowed Professorship
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Ophthalmology-Departmental
草榴社区入口
Houston, TX United States
Education
- MD from State University of Campinas-UNICAMP
- 12/1994 - Campinas, Sao Paulo Brazil
- Medicine
- Residency at State University of Campinas-UNICAMP
- 12/1997 - Campinas, Sao Paulo Brazil
- Ophthalmology
- PhD from University of Sao Paulo, Ribeirao Preto
- 10/2015 - Ribeirao Preto, Sao Paulo Brazil
Honors & Awards
- Caroline F. Elles Professorship
- BCM (04/2023)
Professional Interests
- Dry Eye, Ocular Surface Diseases, Animal Models of Sjogren Syndrome, Microbiome, Aging
Professional Statement
Dry eye affects millions of people world-wide. The primary objectives of my research are to investigate the pathogenesis of dry eye-related diseases with the ultimate goal to improve the diagnosis, prognosis, and therapy of dry eye.Websites
Selected Publications
- Zaheer M, Wang C, Bian F, Yu Z, Hernandez H, de Souza RG, Simmons KT, Schady D, Swennes AG, Pflugfelder SC, Britton RA, de Paiva CS. "." JJ Autoimmun.. 2018 Sep;93:45-56. Pubmed PMID:
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- Pelegrino FS, Volpe EA, Gandhi NB, Li DQ, Pflugfelder SC, de Paiva CS. "." Arthritis Res Ther.. 2012;14(6):R234. Pubmed PMID:
- Wang C, Zaheer M, Bian F, Quach D, Swennes AG, Britton RA, Pflugfelder SC, de Paiva CS "." Int J Mol Sci.. 2018 Feb;19(2):E565. Pubmed PMID:
- de Paiva CS, Lindsey JL, Pflugfelder SC "." Ophthalmology. 2003 Jun;110(6):1102-9. Pubmed PMID:
- Stern ME, Schaumburg CS, Siemasko KF, Gao J, Wheeler LA, Grupe DA, De Paiva CS, Calder VL, Calonge M, Niederkorn JY, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2012;53(4):2062-75. Pubmed PMID:
- De Paiva CS, Pflugfelder SC, Li DQ "." Stem Cells. 2006 Feb;24(2):368-75. Pubmed PMID:
- Chen Z, de Paiva CS, Luo L, Kretzer FL, Pflugfelder SC, Li DQ "." Stem Cells. 2004;22(3):355-66. Pubmed PMID:
- De Paiva CS, Yoon KC, Pangelinan SB, Pham S, Puthenparambil LM, Chuang EY, Farley WJ, Stern ME, Li DQ, Pflugfelder SC "." 2009;6:31. Pubmed PMID:
- De Paiva CS, Pflugfelder SC "." Am. J. Ophthalmol.. 2004 Jan;137(1):109-15. Pubmed PMID:
- De Paiva CS, Corrales RM, Villarreal AL, Farley WJ, Li DQ, Stern ME, Pflugfelder SC "." Exp. Eye Res.. 2006 Sep;83(3):526-35. Pubmed PMID:
- Yoon KC, De Paiva CS, Qi H, Chen Z, Farley WJ, Li DQ, Stern ME, Pflugfelder SC "." J. Autoimmun.. 2008 Jun;30(4):212-21. Pubmed PMID:
- Beardsley RM, De Paiva CS, Power DF, Pflugfelder SC "." Cornea. 2008 Sep;27(8):935-40. Pubmed PMID:
- Zhang X, Chen W, De Paiva CS, Volpe EA, Gandhi NB, Farley WJ, Li DQ, Niederkorn JY, Stern ME, Pflugfelder SC "." Am. J. Pathol.. 2011 Oct;179(4):1807-14. Pubmed PMID:
- Niederkorn JY, Stern ME, Pflugfelder SC, De Paiva CS, Corrales RM, Gao J, Siemasko K "." J. Immunol.. 2006 Apr 1;176(7):3950-7. Pubmed PMID:
- Zheng X, de Paiva CS, Li DQ, Farley WJ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2010 Jun;51(6):3083-91. Pubmed PMID:
- Corrales RM, Stern ME, De Paiva CS, Welch J, Li DQ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2006 Aug;47(8):3293-302. Pubmed PMID:
- De Paiva CS, Volpe EA, Gandhi NB, Zhang X, Zheng X, Pitcher JD, Farley WJ, Stern ME, Niederkorn JY, Li DQ, Flavell RA, Pflugfelder SC "." PLoS ONE. 2011;6(12):e29017. Pubmed PMID:
- De Paiva CS, Villarreal AL, Corrales RM, Rahman HT, Chang VY, Farley WJ, Stern ME, Niederkorn JY, Li DQ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2007 Jun;48(6):2553-60. Pubmed PMID:
- Pflugfelder SC, De Paiva CS, Villarreal AL, Stern ME "." Cornea. 2008 Jan;27(1):64-9. Pubmed PMID:
- Kim HH, De Paiva CS, Yen MT "." Can. J. Ophthalmol.. 2007 Oct;42(5):739-42. Pubmed PMID:
- Corrales RM, de Paiva CS, Li DQ, Farley WJ, Henriksson JT, Bergmanson JP, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2011;52(6):3492-9. Pubmed PMID:
- Pflugfelder SC, de Paiva CS, Li DQ, Stern ME "." Cornea. 2008 Sep;27:S9-11. Pubmed PMID:
- De Paiva CS, Pangelinan SB, Chang E, Yoon KC, Farley WJ, Li DQ, Pflugfelder SC "." Arch. Ophthalmol.. 2009 Dec;127(12):1625-31. Pubmed PMID:
- Zheng X, De Paiva CS, Rao K, Li DQ, Farley WJ, Stern M, Pflugfelder SC "." Cornea. 2010 Sep;29(9):1048-54. Pubmed PMID:
- Tong L, Corrales RM, Chen Z, Villarreal AL, De Paiva CS, Beuerman R, Li DQ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2006 May;47(5):1938-46. Pubmed PMID:
- Yoon KC, De Paiva CS, Qi H, Chen Z, Farley WJ, Li DQ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2007 Jun;48(6):2561-9. Pubmed PMID:
- Alex A, Edwards A, Hays JD, Kerkstra M, Shih A, de Paiva CS, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2013;54(5):3325-32. Pubmed PMID:
- Qi H, Shine HD, Li DQ, de Paiva CS, Farley WJ, Jones DB, Pflugfelder SC "." Exp. Eye Res.. 2008 Dec;87(6):580-6. Pubmed PMID:
- Rocha EM, Pelegrino FS, de Paiva CS, Vigorito AC, de Souza CA "." Bone Marrow Transplant.. 2000 May;25(10):1101-3. Pubmed PMID:
- Alberto-Rincon Mdo C, de Paiva CS, Abrahamsohn PA, Zorn TM "." Acta Anat (Basel). 1994;150(2):119-26. Pubmed PMID:
- De Paiva CS, Raince JK, McClellan AJ, Shanmugam KP, Pangelinan SB, Volpe EA, Corrales RM, Farley WJ, Corry DB, Li DQ, Pflugfelder SC "." Mucosal Immunol. 2011 Jul;4(4):397-408. Pubmed PMID:
- De Paiva CS, Chotikavanich S, Pangelinan SB, Pitcher JD, Fang B, Zheng X, Ma P, Farley WJ, Siemasko KF, Niederkorn JY, Stern ME, Li DQ, Pflugfelder SC "." 2009 May;2(3):243-53. Pubmed PMID:
- Zheng X, Bian F, Ma P, De Paiva CS, Stern M, Pflugfelder SC, Li DQ "." J. Cell. Physiol.. 2010 Jan;222(1):95-102. Pubmed PMID:
- De Paiva CS, Harris LD, Pflugfelder SC "." Cornea. 2003 Jan;22(1):22-4. Pubmed PMID:
- Pelegrino FS, Pflugfelder SC, De Paiva CS "." Exp. Eye Res.. 2012 Jan;94(1):150-6. Pubmed PMID:
- Pflugfelder SC, Farley W, Luo L, Chen LZ, de Paiva CS, Olmos LC, Li DQ, Fini ME "." Am. J. Pathol.. 2005 Jan;166(1):61-71. Pubmed PMID:
- Schaumburg CS, Siemasko KF, De Paiva CS, Wheeler LA, Niederkorn JY, Pflugfelder SC, Stern ME "." J. Immunol.. 2011 Oct 1;187(7):3653-62. Pubmed PMID:
- Li DQ, Chen Z, Song XJ, de Paiva CS, Kim HS, Pflugfelder SC "." Exp. Eye Res.. 2005 Apr;80(4):581-90. Pubmed PMID:
- Qi H, Chuang EY, Yoon KC, de Paiva CS, Shine HD, Jones DB, Pflugfelder SC, Li DQ "." Mol. Vis.. 2007;13:1934-41. Pubmed PMID:
- Pitcher JD, De Paiva CS, Pelegrino FS, McClellan AJ, Raince JK, Pangelinan SB, Rahimy E, Farley WJ, Stern ME, Li DQ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2011;52(6):3221-7. Pubmed PMID:
- Kim HS, Jun Song X, de Paiva CS, Chen Z, Pflugfelder SC, Li DQ "." Exp. Eye Res.. 2004 Jul;79(1):41-9. Pubmed PMID:
- Chotikavanich S, de Paiva CS, Li de Q, Chen JJ, Bian F, Farley WJ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2009 Jul;50(7):3203-9. Pubmed PMID:
- de Paiva CS, Schwartz CE, Gj枚rstrup P, Pflugfelder SC "." Cornea. 2012 Nov;31(11):1299-303. Pubmed PMID:
- Li DQ, Zhang L, Pflugfelder SC, De Paiva CS, Zhang X, Zhao G, Zheng X, Su Z, Qu Y "." J. Allergy Clin. Immunol.. 2011 Dec;128(6):1318-1325.e2. Pubmed PMID:
- Yeh S, de Paiva CS, Hwang CS, Trinca K, Lingappan A, Rafati JK, Farley WJ, Li DQ, Pflugfelder SC "." Br J Ophthalmol. 2009 Sep;93(9):1260-4. Pubmed PMID:
- Pflugfelder SC, de Paiva CS, Tong L, Luo L, Stern ME, Li DQ "." Ocul Surf. 2005 Oct;3(4):S154-7. Pubmed PMID:
- de Paiva CS, Pflugfelder SC "." Exp. Eye Res.. 2004 Mar;78(3):395-7. Pubmed PMID:
- Lam H, Bleiden L, de Paiva CS, Farley W, Stern ME, Pflugfelder SC "." Am. J. Ophthalmol.. 2009 Feb;147(2):198-205. e1. Pubmed PMID:
- De Paiva CS, Chen Z, Koch DD, Hamill MB, Manuel FK, Hassan SS, Wilhelmus KR, Pflugfelder SC "." Am. J. Ophthalmol.. 2006 Mar;141(3):438-45. Pubmed PMID:
- Tong L, Chen Z, De Paiva CS, Beuerman R, Li DQ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2006 Oct;47(10):4295-301. Pubmed PMID:
- Zheng X, Ma P, de Paiva CS, Cunningham MA, Hwang CS, Pflugfelder SC, Li DQ "." Invest. Ophthalmol. Vis. Sci.. 2010 Jun;51(6):3076-82. Pubmed PMID:
- 77. Moore QL, De Paiva CS, Pflugfelder SC "." Am J Ophthalmol. 2015 Jul;160(1):135-142. Pubmed PMID:
- De Paiva CS, Corrales RM, Villarreal AL, Farley W, Li DQ, Stern ME, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2006 Jul;47(7):2847-56. Pubmed PMID:
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- De Paiva CS, Hwang CS, Pitcher JD, Pangelinan SB, Rahimy E, Chen W, Yoon KC, Farley WJ, Niederkorn JY, Stern ME, Li DQ, Pflugfelder SC "." Rheumatology (Oxford). 2010 Feb;49(2):246-58. Pubmed PMID:
- 75. You IC, Bian F, Volpe EA, de Paiva CS, Pflugfelder SC "." Invest Ophthalmol Vis Sci. 2015 Mar; Pubmed PMID:
- de Paiva CS, Chen Z, Corrales RM, Pflugfelder SC, Li DQ "." Stem Cells. 2005;23(1):63-73. Pubmed PMID:
- Ahmad S, Kolli S, Li DQ, de Paiva CS, Pryzborski S, Dimmick I, Armstrong L, Figueiredo FC, Lako M "." Stem Cells. 2008 Jun;26(6):1609-19. Pubmed PMID:
- Deng R, Su Z, Lu F, Zhang L, Lin J, Zhang X, de Paiva CS, Pflugfelder SC, Li DQ. "." Exp Eye Res. 2014;. 2014;120(118):26. 29. Pubmed PMID:
- Lin J, Yoon KC, Zhang L, Su Z, Lu R, Ma P, De Paiva CS, Pflugfelder SC, Li DQ "." PLoS ONE. 2012;7(11):e49571. Pubmed PMID:
- Pflugfelder SC, Maskin SL, Anderson B, Chodosh J, Holland EJ, De Paiva CS, Bartels SP, Micuda T, Proskin HM, Vogel R "." Am. J. Ophthalmol.. 2004 Sep;138(3):444-57. Pubmed PMID:
- "." J Immunol. 2014 Nov 15;.;193(10):5264-72.. Pubmed PMID:
- "Desiccating Stress-Induced MMP Production and Activity Worsens Wound Healing in Alkali-Burned Corneas." ;
- 80. Coursey TG, Henriksson JT, Marcano DC, Shin CS, Isenhart LC, Ahmad F, De Paiva CS, Pflugfelder SC, Acharya G "." J Control Release. 2015; Pubmed PMID:
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- Zhang X, Chen W, De Paiva CS, Corrales RM, Volpe EA, McClellan AJ, Farley WJ, Li DQ, Pflugfelder SC "." Invest. Ophthalmol. Vis. Sci.. 2011 Sep;52(9):6279-85. Pubmed PMID:
- "." Arch Immunol Ther Exp (Warsz). 2015 Mar 13.. 2015 Mar; Pubmed PMID:
- Coursey TG, de Paiva CS "." Clin Ophthalmol.. 2014; Pubmed PMID:
- Zhang X, Volpe EA, Gandhi NB, Schaumburg CS, Siemasko KF, Pangelinan SB, Kelly SD, Hayday AC, Li DQ, Stern ME, Niederkorn JY, Pflugfelder SC, De Paiva CS "." PLoS ONE. 2012;7(5):e36822. Pubmed PMID:
- de Paiva CS, Rocha EM "." Curr Opin Ophthalmol.. 2015; Pubmed PMID:
- Rahimy E, Pitcher JD, Pangelinan SB, Chen W, Farley WJ, Niederkorn JY, Stern ME, Li DQ, Pflugfelder SC, De Paiva CS "." Am. J. Pathol.. 2010 Aug;177(2):744-53. Pubmed PMID:
- Suhalim JL, Parfitt GJ, Xie Y, de Paiva CS, Pflugfelder SC, Shah TN, Potma EO, Brown DJ, Jester JV. "." Ocul Surf.. 2014;12(1):59-68. Pubmed PMID:
- McClellan AJ, Volpe EA, Zhang X, Darlington GJ, Li DQ, Pflugfelder SC, de Paiva CS. "." Am J Pathol.. 2014;184(3):631-43. Pubmed PMID:
- Zhang X, de Paiva CS, Su Z, Volpe EA, Li DQ, Pflugfelder SC. "." Exp Eye Res.. 2014;118:117-24. Pubmed PMID:
- Coursey TG, Gandhi NB, Volpe EA, Pflugfelder SC, de Paiva CS. "Chemokine Receptors CCR6 and CXCR3 Are Necessary for CD4(+) T Cell Mediated Ocular Surface Disease in Experimental Dry Eye Disease.." PLoS One. 2013;.;8(11):e78508.
- Zhang X, Schaumburg CS, Coursey TG, Siemasko KF, Volpe EA, Gandhi NB, Li DQ, Niederkorn JY, Stern ME, Pflugfelder SC, de Paiva CS. "." Mucosal Immunol.. 2014;7(2):417-27. Pubmed PMID:
- Pflugfelder SC, Corrales RM, de Paiva CS. "." Exp Eye Res.. 2013;117:118-25. Pubmed PMID:
- Gandhi NB, Su Z, Zhang X, Volpe EA, Pelegrino FS, Rahman SA, Li DQ, Pflugfelder SC, de Paiva CS. "." J Leukoc Biol.. 2013;94(6):1293-301. Pubmed PMID:
- Alex A, Edwards A, Hays JD, Kerkstra M, Shih A, de Paiva CS, Pflugfelder SC. "." Invest Ophthalmol Vis Sci.. 2013;54(5):3325-82. Pubmed PMID:
- Su Z, Lin J, Lu F, Zhang X, Zhang L, Gandhi NB, de Paiva CS, Pflugfelder SC, Li DQ. "." Mucosal Immunol.. 2013;6(5):921-30. Pubmed PMID:
- Lin J, Yoon KC, Zhang L, Su Z, Lu R, Ma P, de Paiva CS, Pflugfelder SC, Li DQ. "." PLoS One. 2012;7(11):e49571. Pubmed PMID:
- Henriksson JT, de Paiva CS, Farley W, Pflugfelder SC, Burns AR, Bergmanson JP. "." Cornea. 2013;32(4):483-90. Pubmed PMID:
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Funding
- COMMENSAL MICROBIOTA MODULATES OCULAR SURFACE MUCOSAL INFLAMMATION - #R01EY026893 (09/01/2017 - 08/31/2022) Grant funding from NIH-NEI
- Defining the interplay of interferon-gamma and cathepsin S in age-related dry eye - #5R01EY030447-03 (09/01/2018 - 06/01/2024) Grant funding from NIH/NEI
- Programmable Microwafer Drug Delivery System for Ocular Injuries - #W81XWH-12-1-0616 (09/01/2012 - 09/30/2016) Grant funding from DoD
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