Current and On-going Solicitations
The Translational Research Institute for Space Health offers multiple funding mechanisms with variable solicitation methods, funding amounts, durations and review cycles. TRISH's research priorities include commercial space health research (EXPAND), medical system architecture (HERMES), and tissues-chips (SENTINEL). View our current solicitations below.
Remote Biomarker Measurements in Microphysiological Systems

TRISH is seeking proposals to advance remote biomarker analysis capabilities in microphysiological systems (MPS), also known as tissue chips, for space exploration. This solicitation aims to support innovative solutions to improve in-situ measurement technologies for use during future deep space missions, where traditional sample return back to Earth may not be feasible.
Proposals will focus on technologies capable of analyzing a wide range of biomarkers, bioindicators or biosignatures without requiring sample return. TRISH is prioritizing methods that are non-invasive, that do not destroy the sample, and allow for data collection over multiple timepoints separated by days or weeks. Such systems should be adaptable and not restricted to specific laboratory setups. In addition to biomarkers, proposers may address environmental factors, cell function, and tissue health in advanced biological constructs.
By advancing tissue chip technology, TRISH aims for a new way to gather personalized astronaut data without needing a human to tend the samples.
The deadline to submit proposals has been extended to 11:59 p.m. ET on March 13, 2025.
Deadline to submit: 11:59 p.m. CT on March 6, 2025
Proposals addressing these subjects will receive higher priority:
- Advancing technology to support remote crew health and performance monitoring
- Advancing remote healthcare knowledge base
- Advancing remote research capabilities
Tier 1 projects are a maximum total amount < $150K and limited to one year. Tier 2 projects can reach a total amount of ≥ $150K for up to two years.