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Center for Space Medicine

TRISH Funding Opportunities and Awards

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Remote Biomarker Measurements in Microphysiological Systems

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TRISH Remote Biomarkers Solicitation
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TRISH is seeking proposals to advance remote biomarker analysis capabilities in microphysiological systems (MPS), also known as tissue chips, for space exploration. This solicitation aims to support innovative solutions to improve in-situ measurement technologies for use during future deep space missions, where traditional sample return back to Earth may not be feasible.

Proposals will focus on technologies capable of analyzing a wide range of biomarkers, bioindicators or biosignatures without requiring sample return. TRISH is prioritizing methods that are non-invasive, that do not destroy the sample, and allow for data collection over multiple timepoints separated by days or weeks. Such systems should be adaptable and not restricted to specific laboratory setups. In addition to biomarkers, proposers may address environmental factors, cell function, and tissue health in advanced biological constructs.

By advancing tissue chip technology, TRISH aims for a new way to gather personalized astronaut data without needing a human to tend the samples.

The deadline to submit proposals has been extended to 11:59 p.m. ET on March 13, 2025.

. Outside the box thinking is encouraged to advance the future of spaceflight and it is expected that technology and innovations developed to positively impact space health will also translate to support health care on the ground, especially in remote or rural environments. Topics and focus areas of interest are discussed in the solicitation document.

Deadline to submit: 11:59 p.m. CT on March 6, 2025

may be proposed. However, TRISH has identified three topic areas of high interest, each encompassing several sub-topics.

Proposals addressing these subjects will receive higher priority:

  • Advancing technology to support remote crew health and performance monitoring
  • Advancing remote healthcare knowledge base
  • Advancing remote research capabilities

Tier 1 projects are a maximum total amount < $150K and limited to one year. Tier 2 projects can reach a total amount of ≥ $150K for up to two years.

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